Publications by authors named "Charlien Hupko"
Article Synopsis
- Azithromycin has been identified as a viable treatment option for invasive non-typhoidal Salmonella (iNTS) infections, and researchers established its epidemiological cut-off (ECOFF) to assess susceptibility.
- The study involved testing various methods of measuring azithromycin susceptibility across 515 iNTS isolates from blood cultures in several countries, using techniques like broth microdilution, agar dilution, and disk diffusion.
- Results showed that the ECOFF for azithromycin was 16 mg/L, and while disk diffusion proved to be an accurate alternative, gradient tests performed better when read at 100% inhibition rather than 80%.
Invasive pulmonary aspergillosis (IPA) caused by the mold Aspergillus fumigatus is one of the most important life-threatening infections in immunocompromised patients. The alarming increase of isolates resistant to the first-line recommended antifungal therapy urges more insights into triazole-resistant A. fumigatus infections.
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