Publications by authors named "Charlie McKenna"
J Thromb Haemost
August 2023
Article Synopsis
- Platelet function varies widely among individuals, and current tests typically measure only the end-point activation levels without considering how quickly platelets activate, which might overlook important details about their reactivity.
- A new real-time flow cytometry method was developed to assess the speed of platelet activation, identifying distinct rates of response to different activating agents that do not necessarily relate to maximum activation levels.
- Findings show that faster platelet responses correlate with larger and denser blood clots in arterial conditions, suggesting that the activation rate should be considered in future antiplatelet therapies to enhance effectiveness while minimizing bleeding risk.
