Publications by authors named "Charlie J Clarke-Williams"
Article Synopsis
- Certain memories can persist and influence harmful behaviors due to their strong connections across various brain regions.
- Researchers studied multiple areas of the mouse brain to understand how these memories are retrieved and maintained, particularly focusing on experiences related to cocaine.
- They discovered that a specific pattern of brain activity, coordinated across different networks during memory recall, is key to how persistent memories operate and can potentially be manipulated to prevent relapse into drug-related behaviors.
This Formal Comment responds to Jordan et al., and stresses that if scientific findings are to be robust, training in experimental design and statistics is critical to ensure that research questions, design considerations, and analyses are aligned.
View Article and Find Full Text PDFBiologists determine experimental effects by perturbing biological entities or units. When done appropriately, independent replication of the entity-intervention pair contributes to the sample size (N) and forms the basis of statistical inference. If the wrong entity-intervention pair is chosen, an experiment cannot address the question of interest.
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