Publications by authors named "Charlie Hart"

Article Synopsis
  • The study investigates bat-borne coronaviruses in the UK, screening 48 faecal samples from various bat species.
  • Researchers identified nine complete coronavirus genomes, including two new species, highlighting a range of coronaviruses such as alphacoronaviruses and a MERS-related betacoronavirus.
  • One sarbecovirus was found to bind the human ACE2 receptor, indicating potential for human infection, but further mutations are needed for enhanced infectivity, stressing the importance of monitoring these viruses due to their zoonotic risk.
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Plant cell walls are complex matrixes of heterogeneous glycans which play an important role in the physiology and development of plants and provide the raw materials for human societies (e.g. wood, paper, textile and biofuel industries)(1,2).

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Human platelet-derived growth factor-BB (hPDGF-BB) is a basic polypeptide growth factor released from platelets at the injury site. It is a multifunctional molecule that regulates DNA synthesis and cell division and induces biological effects that are implicated in tissue repair, atherosclerosis, inflammatory responses, and neoplastic diseases. This paper is an overview of the toxicology data generated from a broad testing platform to determine bone, soft tissue, and systemic responses following administration of rhPDGF-BB.

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