Publications by authors named "Charlie DeCamp"

The objective of this study was to compare longitudinal results from two models of combined anterior cruciate ligament (ACL) and meniscal injury. A modified ACL transection (mACLT) model and a traumatic impact (ACLF) model were used to create an ACL rupture and acute meniscal damage in a Flemish Giant animal model. The animals were euthanized at time points of 4, 8, or 12 weeks.

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Article Synopsis
  • Subchondral bone is crucial in the development of post-traumatic osteoarthritis, and this study aimed to observe its changes following ACL injuries in rabbits using two different models.
  • Twelve weeks after injury, scans revealed that both models showed decreased bone volume and mineral density in the affected bones.
  • The study found distinct patterns of bone changes based on the injury type, suggesting that soft tissue damage and impact forces play key roles in these alterations.
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Post-traumatic osteoarthritis (PTOA) develops as a result of traumatic loading that causes tears of the soft tissues in the knee. A modified transection model, where the anterior cruciate ligament (ACL) and both menisci were transected, was used on skeletally mature Flemish Giant rabbits. Gross morphological assessments, elastic moduli, and glycosaminoglycan (GAG) coverage of the menisci were determined to quantify the amount of tissue damage 12 weeks post injury.

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Objective: To evaluate the effect of limb positioning and measurement technique on the magnitude of the radiographically determined tibial plateau angle (R-TPA).

Study Design: In vitro study, R-TPA was determined by 6 blinded observers and image measurement software.

Animals: Five canine cadaver hind limbs.

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