Publications by authors named "Charley Jin"
Article Synopsis
- Social jetlag refers to the gap between sleep times on workdays versus weekends, which can negatively impact sleep quality and increase daytime sleepiness, especially in individuals with obstructive sleep apnea (OSA).
- A study involving over 2,000 participants found that a significant portion experienced varying degrees of social jetlag, with those having 2 or more hours of jetlag reporting higher daytime sleepiness scores.
- The research suggests that addressing social jetlag could be a beneficial strategy for managing daytime sleepiness in people with OSA, particularly in those with mild cases.
Obstructive sleep apnea (OSA) affects a significant proportion of the population and is linked to increased rates of cancer development and a worse cancer outcome. OSA is characterized by nocturnal intermittent hypoxia and animal models of OSA-like intermittent hypoxia show increased tumor growth and metastasis. Advanced tumors typically have regions of chronic hypoxia, activating the transcription factor, HIF-1, which controls the expression of genes involved in cancer progression.
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