Vaginal progesterone for prevention of preterm birth in women with a history of preterm birth regardless of cervical length: an argument for use.

It is well understood that preterm birth accounts for a substantial amount of poor neonatal outcomes. In 2022, preterm birth affected about 1 of every 10 infants born in the United States with complications ranging from mild respiratory distress syndrome to neonatal death. The complexity of the treatment is secondary to the fact that preterm birth is a multifactorial syndrome with intricate sociocultural factors that influence our racially disproportionate poor outcomes.

Florida Doulas' Perspectives on Their Role in Reducing Maternal Morbidity and Health Disparities.

Background: Maternal mortality rates continue to rise in the United States. Considerable racial disparities exist, as Black women face two to three times the risks of dying from pregnancy-related complications compared with white women. Doulas have been associated with improved maternal outcomes.

Adverse Childhood Experiences Are Associated with Cardiometabolic Risk among Hispanic American Adolescents.

Objective: To assess the relationship between adverse childhood experiences (ACEs) and cardiometabolic risk among Hispanic adolescents.

Study Design: This cross-sectional study was conducted at an academic research center in Gainesville, Florida. Participants were locally recruited, and data were collected from June 2016 to July 2018.

Identification of a molecular basis for the juvenile sleep state.

Across species, sleep in young animals is critical for normal brain maturation. The molecular determinants of early life sleep remain unknown. Through an RNAi-based screen, we identified a gene, , required for sleep maturation in , a transcription factor, coordinates an early developmental program that prepares the brain to later execute high levels of juvenile adult sleep.

Behavioral and genetic features of sleep ontogeny in Drosophila.

The fruit fly Drosophila melanogaster, like most organisms, exhibits increased sleep amount and depth in young compared to mature animals. While the fly has emerged as a powerful model for studying sleep during development, qualitative behavioral features of sleep ontogeny and its genetic control are poorly understood. Here we find that, in addition to increased sleep time and intensity, young flies sleep with less place preference than mature adults, and, like mammals, exhibit more motor twitches during sleep.