Publications by authors named "Charles Rene Leemans"

Background: The purpose of this study was to investigate unmet supportive care needs in patients treated with total laryngectomy and its associated factors.

Methods: In this cross-sectional study, 283 patients who underwent total laryngectomy completed questions on supportive care needs (Supportive Care Needs Survey [SCNS]). Median time since total laryngectomy surgery was 7 years (range 0-37 years).

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Purpose: The aim of this study was to clinically validate a multivariable normal tissue complication probability (NTCP) model for grade 2-4 swallowing dysfunction at 6months after radiotherapy or chemoradiation (SWALM6) in head and neck cancer patients treated with swallowing sparing intensity modulated radiotherapy (SW-IMRT) and to test if SW-IMRT resulted in a reduction of the prevalence of SWALM6.

Materials And Methods: The primary endpoint was SWALM6. For all 186 patients, a standard IMRT (parotid sparing) and a SW-IMRT plan (additional constraints for swallowing organs at risk) was created.

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Purpose Of Review: This paper reviews the advances in surgery in head and neck cancer patients.

Recent Findings: Sentinel node biopsy is a promising diagnostic technique to detect occult lymph node metastases, especially in oral carcinomas. Fludeoxyglucose-PET seems to be useful in detecting recurrent (laryngeal) carcinoma after radiotherapy.

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In subtotal nose reconstruction, different tissues have to be reconstructed. We report the case of a 51-year-old man with a severe deformity of the nose (shortening and collapse of the nose, retraction of the right alar area, and a total septal defect after surgery and radiotherapy for a septum nasi carcinoma). Reconstruction with good results was performed with a "gangplank" flap technique (using a U-shaped skin flap for inner lining and for lengthening), rib cartilage for the nasal skeleton, and skin coverage with a paramedian forehead flap.

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