A randomized controlled clinical trial of 2295 ultrasound-guided embryo transfers.

Background: We wanted to test the hypothesis that using abdominal ultrasound at the time of embryo transfer to guide replacement, improved pregnancy rates by at least 5%.

Methods: An RCT in a large assisted conception unit. A pilot study and power calculation suggested that at least 2000 embryo transfers were required to demonstrate a difference of 5%, for a test with 80% power and Type 1 error 0.

Gynaefix frameless IUD: Cause of bowel resection.

A case of a lost GyneFix intrauterine contraceptive device (IUD) is described, in which laparoscopy failed to identify the device and laparotomy had to be carried out to remove the IUD, which was embedded in the small bowel necessitating bowel resection. Awareness of this complication is necessary, and advanced training is required in order to minimize risks. A description of the GyneFix device, the possible adverse effects and incidence of complications, the importance of post-insertion follow-up, and the need for awareness of the possibility of migration through the bowel are discussed.

Do lunar phases affect conception rates in assisted reproduction?

Objectives: To assess the effect of the phases of the moon on pregnancy rates in humans following in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatment.

Design: Retrospective, observational study.

Setting: Reproductive Medicine Unit, Liverpool Women's Hospital.

National survey of current practice in assessing tubal patency in the UK.

We conducted a postal survey to find out the current practice in the UK regarding the methods employed to assess tubal patency. A questionnaire was developed to evaluate the methods used to assess tubal patency in women presenting with infertility with or without risk factors suggesting pelvic disease. A total of 496 questionnaires were sent and 174 responded (35%).

A potential new use for gonadotropin-releasing hormone antagonists.

Objective: To describe a potential new use of gonadotropin-releasing hormone (GnRH) antagonists.

Design: Case report.

Setting: Assisted conception unit at a teaching hospital in the United Kingdom.