Elevated oxidative stress and endothelial dysfunction in right coronary artery of right ventricular hypertrophy.

Remodeling of right coronary artery (RCA) occurs during right ventricular hypertrophy (RVH) induced by banding of the pulmonary artery (PA). The effect of RVH on RCA endothelial function and reactive oxygen species (ROS) in vessel wall remains unclear. A swine RVH model (n = 12 pigs) induced by PA banding was used to study RCA endothelial function and ROS level.

A comparative analysis of coronary and aortic flow waveforms.

Empirical Mode decomposition (EMD) is a mathematical tool designed to analyze non-stationary, non-linear stochastic waves. EMD separates a waveform into its constituent modes of oscillations or intrinsic mode functions (IMFs) and provides meaningful definitions of instantaneous frequency, instantaneous energy, mean trends and oscillation about the mean trends. This study provides a detailed mathematical analysis of blood flow waveforms in the porcine left anterior descending artery and aorta using EMD.