Publications by authors named "Charles Peltier"

Background: Ruptured middle cerebral artery aneurysm (MCAa) with intraparenchymal hematoma (IPH) can benefit at the same time from evacuation of the hematoma and exclusion of the aneurysm of a decompressive craniectomy (DC). To date, there are no clear recommendations for performing a DC in such cases.

Methods: We retrospectively collected data from nine French neurosurgical units from January 1, 2013 to December 31, 2020.

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Article Synopsis
  • Ruptured middle cerebral artery aneurysms (MCAa) can cause serious brain bleeding (intracerebral hematoma), and the study aimed to compare the outcomes of two treatments: microsurgery (clipping) and endovascular therapy (EVT).
  • The research involved 162 adult patients who needed evacuation of intracerebral hematoma across nine hospitals in France, analyzing factors linked to recovery using a standard scale (modified Rankin scale) after six months.
  • Results showed that clipping was associated with better functional outcomes (30% poor outcome rate) compared to EVT (76% poor outcome rate), potentially due to longer delays in treatment for the EVT group.
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Purpose: To evaluate the efficacy and safety of a second course of stereotactic radiotherapy (SRT2) treatment for a local recurrence of brain metastases previously treated with SRT (SRT1), using the Hypofractionated Treatment Effects in the Clinic (HyTEC) reporting standards and the European Society for Radiotherapy and Oncology guidelines.

Methods: From December 2014 to May 2021, 32 patients with 34 brain metastases received salvage SRT2 after failed SRT1. A total dose of 21 to 27 Gy in 3 fractions or 30 Gy in 5 fractions was prescribed to the periphery of the PTV (99% of the prescribed dose covering 99% of the PTV).

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