Extracts of Leptadenia hastata Leaf, a Famine Food and Traditional Remedy for Furuncles, Suppress Inflammation in Murine Models.

The effects of the methanol extract (LHE), hexane (LHHF), ethylacetate (LHEF) and methanol (LHMF) fractions of leaf of Leptadenia hastata on acute and chronic inflammation were studied. Furthermore, the effects of LHE on acetic acid induced increase in vascular permeability, carrageenan induced leucocyte migration and membrane stability were evaluated. The LHE and fractions were also subjected to phytochemical analysis.

Antimicrobial Effects of a Lipophilic Fraction and Kaurenoic Acid Isolated from the Root Bark Extracts of Annona senegalensis.

Root bark preparation of Annona senegalensis Pers. (Annonaceae) is used in Nigerian ethnomedicine for treatment of infectious diseases. Extraction of the A.

Studies on the antiulcer and gastrointestinal effects of stem bark extract of Bridelia ferruginea.

The antiulcer and gastrointestinal effects of methanol stem bark extract (BFME) of Bridelia ferruginea Benth. (Euphorbiaceae) and its solvent fractions-dichloromethane (DCMF) and methanol (MF)-were studied using indomethacin- and ethanol-induced ulcers in rats, small intestinal transit of charcoal meal in mice, and the effects on acetylcholine-induced contractions of the isolated guinea pig ileum. The extract and fractions significantly (P<0.

The anti-inflammatory and antinociceptive properties of the chloroform fraction from Phyllanthus niruri plant is mediated via the peripheral nervous system.

Phyllanthus niruri (Euphorbiaceae) is used folklorically for the treatment of diabetes, malaria, fever, diarrhea, liver disease, and urolithiasis. As an initial step toward isolating compounds effective against inflammation and pain, this study is aimed at providing scientific evidence for the anti-inflammatory, antinociceptive, and antipyretic properties of the chloroform soluble fraction (PNF1) of Phyllanthus niruri methanol extract in rats and mice. Three doses of PNF1 [25, 50, 100 mg/kg body weight (bw)] were used.