Publications by authors named "Charles Mutinda"
We aimed to establish if enteric permeability was associated with similar biological processes in children recovering from hospitalization and relatively healthy children in the community. Extreme gradient boosted models predicting the lactulose-rhamnose ratio (LRR), a biomarker of enteric permeability, using 7,500 plasma proteins and 34 fecal biomarkers of enteric infection among 89 hospitalized and 60 community children aged 2-23 months were built. The R values were calculated in test sets.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to investigate the link between gut permeability and growth/inflammation in hospitalized children from low- and middle-income countries.
- It involved testing the gut permeability of young hospitalized children and comparing results to those of children from their communities, using various statistical models to analyze the data.
- Although hospitalized children showed higher gut permeability, it did not correlate with significant changes in their growth after discharge, and differences in systemic inflammation indicators were noted between the two groups.
Article Synopsis
- The study focused on developing and testing high-yielding, stress-tolerant maize hybrids in eastern Africa to boost productivity for smallholder farmers.
- The trials were conducted across four countries (Kenya, Uganda, Tanzania, and Rwanda) with a significant number of participating farmers, revealing that these new hybrids performed better in low-yielding conditions compared to existing commercial varieties.
- Farmers prioritized grain yield in their selection process, highlighting the importance of these new hybrids for improved agricultural outcomes under varying environmental stresses.
A nuclear-gene mutation of the C3 grass Lolium temulentum L., which arose following cell suspension culture and plant regeneration, is manifested as delayed and incomplete greening, which occurs from the leaf tip downwards. Many plastids in the mutant exhibit abnormal morphology when examined by transmission electron microscopy; the plastid outer envelope lacks integrity and thylakoids, while still stacked, are spread over a wide area surrounded by diffuse stromal contents.
View Article and Find Full Text PDF