Single-fraction image-guided extracranial radiosurgery for recurrent and metastatic abdominal and pelvic cancers: short-term local control, metabolic response, and toxicity.

Purpose: Extracranial radiosurgery (ECRS) is a novel treatment for inoperable recurrent or metastatic abdominopelvic cancers. However, local control, metabolic response, and acute toxicity remain undefined. We therefore analyzed these endpoints in patients treated with single-fraction image-guided ECRS at Emory University.

Prognostic accuracy of computed tomography findings for patients with laryngeal cancer undergoing laryngectomy.

Purpose: The indications for upfront laryngectomy in the management of laryngeal cancer are a functionless larynx and extralaryngeal extension. Practically, clinicians rely on imaging to predict which patients will have T4 disease. Our goal was to review the accuracy of preoperative computed tomography (CT) scanning in determining the necessity for initial laryngectomy for advanced laryngeal cancer.

Image-guided radiation therapy (IGRT) in gastrointestinal tumors.

Context: Daily setup errors and changes in body habitus during external beam radiotherapy can result in interfraction variation, contributing to uncertainties in treatment delivery. The conventional method of patient positioning using external skin markings is inadequate in reducing these interfraction variations.

Objective: To evaluate use of on-board imaging with daily kV-kV image matching to reduce interfraction variation in patients with primary gastrointestinal cancer.