Brain natriuretic peptide and biomarkers of myocardial ischemia increase after defibrillation threshold testing.

Background: During implantable cardioverter defibrillator insertion, induced ventricular fibrillation followed by test shocks (defibrillation threshold testing [DFT]) is utilized to confirm effective device function. The effect of DFT on ventricular function is uncertain. Brain natriuretic peptide (BNP) is a marker of ventricular dysfunction and hemodynamic stress.

Quality of cardiovascular care in an internal medicine resident clinic.

Background: Attainment of treatment goals derived from evidence-based practice guidelines can be a useful measure of the quality of cardiovascular care. To date, there are few studies of the quality of care provided in a resident continuity clinic, as measured by success in meeting nationally defined guidelines for control of cardiovascular risk factors. There also is limited information regarding the quality of care in resident continuity clinics serving multiethnic uninsured/underinsured populations.

Disparity in frequency of normal coronary artery in black and white patients undergoing cardiac catheterization.

Background: Normal epicardial coronary arteries (NCA) based on angiography have been reported to occur more frequently in Blacks than in Whites, but these studies have suffered from the limitation of being retrospective, reporting on relatively small numbers of subjects, or lacking a systematic angiogram interpretation.

Methods And Results: Angiograms of 560 consecutive patients (226 Black and 334 White) enrolled in the Harlem-Bassett Study were reviewed. The presence of coronary artery disease risk factors was documented.

Comparative frequency of angiographic coronary artery disease in African Americans and Hispanics.

Background: African Americans and Hispanics are the two largest racial minority groups in the United States. Both groups have a high prevalence of cardiovascular disease risk factors, and African Americans have the highest mortality from cardiovascular disease of any racial group in the United States. Whereas a large body of clinical data compares African Americans and Whites or Hispanics and Whites with regard to coronary artery disease (CAD), limited data are available for such comparison between African Americans and Hispanics.

Heart Failure in Elderly African-Americans.

Heart failure has emerged as one of the most important cardiovascular diseases in the elderly and has a major functional, economic, and social impact in older individuals. Racial differences in the morbidity and mortality, as well as in rates of hospitalization, have been reported in national surveys and epidemiologic studies. Because of the higher prevalence of hypertension and left ventricular hypertrophy in African-Americans compared to whites, these risk factors may be the principle determinants of the hemodynamic and clinical features of heart failure in African-Americans.

Hemodynamic Predictors of Atherosclerosis in the Thoracic Aorta.

We sought to identify atherosclerotic plaques and measured flow parameters in the descending aorta (DA) of 83 consecutive patients (40 years and older) studied with transesophageal echocardiography. Patients with atherosclerotic plaques in the DA were older (68 +/- 10 vs 58 +/- 12 years [P = 0.0001]), had a higher proportion of spontaneous echo contrast in the DA (15/46 [33%] vs 3 of 37 [8%] P = 0.