Publications by authors named "Charles Henri Bretagne"

Introduction: In order to validate our strategy of continuous improvement and to identify new ways to increase performance, an evaluation of all the procedures was conducted in our department using the principles of lean management.

Material And Methods: Lean-6-sigma methodology (Gemba Walk, Value StreamMapping, spaghetti diagram, Kaizen workshop and priorization matrix) was used to analyze the procedures of the conventional and molecular sectors, and to identify bottlenecks, actions without added value and solutions.

Results: The audit identified bottlenecks in pre-analytical (registration), analytical (cytology, immunohistochemistry, sequencing, pathologists) and post-analytical processes (absence of secretaries, delivery of reports by mail).

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Article Synopsis
  • * HPV DNA was found in 34% of patients, with high-risk HPV (HR-HPV) detected in 18%, notably more prevalent among women (23.1%) and individuals with Crohn's disease (30%).
  • * Factors such as female sex, history of STDs, number of sexual partners, smoking, and immunosuppressive therapies were identified as independent risk factors for HR-HPV infection, highlighting the need for better awareness and understanding of this health issue.
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Peritoneal malignant mesothelioma is a rare and extremely aggressive tumor that is sometimes difficult to diagnose. We report two cases of metastatic malignant peritoneal mesothelioma. In one case, malignant metastatic cells were identified in cervical lymph nodes while in the other case, the cells were found in the liver.

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