Crystal structure, Hirshfeld surface analysis and DFT studies of 2-(2,3-di-hydro-1-perimidin-2-yl)phenol.

The asymmetric unit of the title compound, CHNO, contains two independent mol-ecules each consisting of perimidine and phenol units. The tricyclic perimidine units contain naphthalene ring systems and non-planar CN rings adopting envelope conformations with the C atoms of the NCN groups hinged by 44.11 (7) and 48.

Crystal structure, Hirshfeld surface analysis and inter-action energy and DFT studies of 2-(2,3-di-hydro-1-perimidin-2-yl)-6-meth-oxy-phenol.

The title compound, CHNO, consists of perimidine and meth-oxy-phenol units, where the tricyclic perimidine unit contains a naphthalene ring system and a non-planar CN ring adopting an envelope conformation with the NCN group hinged by 47.44 (7)° with respect to the best plane of the other five atoms. In the crystal, O-H⋯N and N-H⋯O (Phnl = phenol and Prmdn = perimidine) hydrogen bonds link the mol-ecules into infinite chains along the -axis direction.

Chemical findings and in vitro biological studies to uphold the use of Ficus exasperata Vahl leaf and stem bark.

Ficus exasperata Vahl, commonly known as sandpaper, is a terrestrial Afro-tropical tree used in popular medicine. Despite the existence of some works on the biological activities of this species, its chemical composition is still poorly known. The aim of this study was to extend the knowledge on the phytochemistry and biological properties of this species.