Publications by authors named "Charles Gregory Elliott"

Article Synopsis
  • Findings show that enlarged pulmonary artery diameter (PAd) and increased pulmonary artery to ascending aorta ratio (PA:AA) on CT scans can indicate higher mortality in certain cardiopulmonary disease patients.
  • In a study of 990 emergency department patients, 27.9% had enlarged PAd, particularly among older individuals and those with obesity or heart failure, while 34.2% had an increased PA:AA, more common in younger patients with peripheral vascular disease or obesity.
  • Both enlarged PAd and increased PA:AA were independently linked to increased mortality risk, highlighting their significance as prognostic indicators in the emergency setting.
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This article provides an overview of pulmonary arterial hypertension (PAH), beginning with the initial pathologic recognition of pulmonary hypertension more than 100 years ago and progressing to the current diagnostic categorization of PAH. It reviews the epidemiology, pathophysiology, genetics, and modern treatment of PAH. The article discusses several important recent studies that have highlighted the importance of new management strategies, including serial risk assessment and combination pharmacotherapy.

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This article provides an overview of pulmonary veno-occlusive disease (PVOD) and pulmonary capillary hemangiomatosis (PCH), two disorders that challenge clinicians, radiologists, and pathologists because they often mimic pulmonary arterial hypertension (PAH). The article reviews the features that differentiate PVOD and PCH from PAH. The article also describes the overlap of PVOD and PCH, highlighted by recent reports of families diagnosed with PVOD or PCH caused by EIF2AK4 mutations.

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