Dyadic Resistance in Parent-Adolescent Interactions During the Transition to High School.

Introduction: Although prior research has examined adolescents' resistance to parental control, the dyadic level of analysis has been overlooked. This study attended to how a Canadian sample of parents and adolescents engaged in resisting one another by observing moment-to-moment actions as they discussed the upcoming transition to high school.

Methods: A secondary analysis of data collected from 2010 to 2012 using the Action-Project Method was conducted.

Impact of COVID-19 on social work field education: Perspectives of Canadian social work students.

Summary: Social work field education has experienced major disruptions due to the COVID-19 pandemic, while also embracing new opportunities to grow. The Transforming the Field Education Landscape research partnership developed a cross-sectional web-based survey with closed- and open-ended questions to understand student perceptions of COVID-19's impacts on social work field education. The survey opened during the first wave of the pandemic from July 8 to 29, 2020 and was completed by 367 Bachelor of Social Work (BSW) and Master of Social Work (MSW) students across Canada.

Results and analysis of an intercomparisons study for individual monitoring services of Latin American and Caribbean regions.

The aim of this paper is to present the results obtained by the Latin-American and Caribbean personal dosimetry services that participated, with the support of IAEA, in the 2020-Eurados whole-body dosemeter intercomparison for photon radiation. All participant services in this study use thermoluminescent dosimetry (TLD) systems except one that uses optically stimulated luminescence (OSL) dosemeters. Data analysis shows that 93.

Overexpression of the UDP-glycosyltransferase UGT34A23 confers resistance to the diamide insecticide chlorantraniliprole in the tomato leafminer, Tuta absoluta.

The tomato leafminer, Tuta absoluta, is an invasive crop pest that has evolved resistance to many of the insecticides used for its control. To facilitate the investigation of the underpinning mechanisms of resistance in this species we generated a contiguous genome assembly using long-read sequencing data. We leveraged this genomic resource to investigate the genetic basis of resistance to the diamide insecticide chlorantraniliprole in Spanish strains of T.

The Crux Toolkit for Analysis of Bottom-Up Tandem Mass Spectrometry Proteomics Data.

The Crux tandem mass spectrometry data analysis toolkit provides a collection of algorithms for analyzing bottom-up proteomics tandem mass spectrometry data. Many publications have described various individual components of Crux, but a comprehensive summary has not been published since 2014. The goal of this work is to summarize the functionality of Crux, focusing on developments since 2014.

Time to act: Early experience suggests stabilization care offers a feasible approach for adolescents after acute life-threatening opioid toxicity.

British Columbia is the epicentre of the opioid crisis in North America. Illicit drug toxicity is now one of the top 3 causes of death for adolescents in British Columbia. Evidence informed treatment is available but adolescents rarely receive it.

A pilot study on the use of neutron activation analysis and multivariate statistics for the provenance of Jamaican Cannabis sativa L (Marijuana).

The aim of this study was to use instrumental neutron activation analysis and multivariate analysis to determine the provenance of Jamaican Cannabis sativa L. Sixty-three samples were collected from various areas in Jamaica, with no other data but their known or self-reported growing regions. The samples were analysed for Al, As, Br, Ca, Cd, Co, Cs, Fe, K, La, Mg, Mn, Na, Rb, Sb, Sc, Sm, Sr, V, and Zn.

Atmospheric dispersion modeling for an accidental release from a SLOWPOKE-2 research reactor: a case study.

Atmospheric dispersion modeling was performed for a postulated design basis accident at a SLOWPOKE research reactor. The MCNP-5 computer code was used to estimate the neutron flux spectrum which was then used in the ORIGEN-S code to perform core depletion calculations and determine the radiological source term. The HotSpot health physics code was then used to model the atmospheric transport of the radioactive material released to estimate the resulting doses to the population downwind of the reactor.

Challenges in the control of neglected insect vector diseases of human importance in the Anglo-Caribbean.

Introduction: Neglected tropical diseases (NTDs) in developing countries like the Caribbean, negatively affect multiple income-generating sectors, including the tourism industry upon which island states are highly dependent. Insect-transmitted NTDs include, but are not limited to, malaria, dengue and lymphatic filariasis. Control measures for these disease, are often ignored because of the associated cost.

Parthenogenesis in UK field populations of the tomato leaf miner, Tuta absoluta, exposed to the mating disruptor Isonet T.

Background: The tomato leafminer, Tuta absoluta is a damaging pest of tomato crops worldwide. In the UK T. absoluta is controlled using an integrated pest management (IPM) strategy that includes pheromone-based mating disruption.

Stigma in relation to families living with parental mental illness: An integrative review.

Stigma is a pervasive social mechanism with negative ramifications for people who experience mental illness. Less is known about the stigma experiences of families where a parent has a mental illness. This review aims to identify and synthesize evidence on the concept of stigma and stigma-related experiences and outcomes reported by parents and children living with parental mental illness.

Carotid Ultrasound to Predict Fluid Responsiveness: A Systematic Review.

Objectives: To perform a systematic review of the accuracy of carotid ultrasound measures in determining volume responsiveness in adults.

Methods: We conducted a systematic review of Ovid MEDLINE and Scopus from conception until January 1, 2019. Two independent reviewers used an iterative process to identify relevant articles and abstract information from them.

T-Gene: improved target gene prediction.

Motivation: Identifying the genes regulated by a given transcription factor (TF) (its 'target genes') is a key step in developing a comprehensive understanding of gene regulation. Previously, we developed a method (CisMapper) for predicting the target genes of a TF based solely on the correlation between a histone modification at the TF's binding site and the expression of the gene across a set of tissues or cell lines. That approach is limited to organisms for which extensive histone and expression data are available, and does not explicitly incorporate the genomic distance between the TF and the gene.

A flavin-dependent monooxgenase confers resistance to chlorantraniliprole in the diamondback moth, Plutella xylostella.

The diamondback moth, Plutella xylostella, is a damaging pest of cruciferous crops, and has evolved resistance to many of the insecticides used for control, including members of the diamide class. Previous work on the molecular basis of resistance to diamides has documented mutations in the target-site, the ryanodine receptor, in resistant populations of P. xylostella worldwide.

The evolution of multiple-insecticide resistance in UK populations of tomato leafminer, Tuta absoluta.

Background: The tomato leafminer, Tuta absoluta, is an economically important pest of tomatoes in Europe, Africa, Asia and South America. In the UK this species is controlled using an integrated pest management (IPM) programme which incorporates the insecticides spinosad and chlorantraniliprole. In response to UK grower concerns of loss of efficacy of these compounds at certain sites, insecticide bioassays were performed on five populations collected from four commercial glasshouses and potential mechanisms of resistance investigated.

MoMo: discovery of statistically significant post-translational modification motifs.

Motivation: Post-translational modifications (PTMs) of proteins are associated with many significant biological functions and can be identified in high throughput using tandem mass spectrometry. Many PTMs are associated with short sequence patterns called 'motifs' that help localize the modifying enzyme. Accordingly, many algorithms have been designed to identify these motifs from mass spectrometry data.

Professionals' Perspectives on Viewing Child Sexual Abuse Images to Improve Response to Victims.

The complexity of the phenomenon of child sexual abuse images online (CSAIO) benefits from cross-disciplinary collaboration across law enforcement, child protection, and children's mental health. Through focus groups with professionals working in these fields, this article focuses on when and whether professionals who work with child sexual abuse cases should be exposed to viewing CSAIO and if so under what circumstances doing so would benefit investigations and support services for victims. In a broader sense, this article is about professional experience, decision making, training, and collaboration around a particularly difficult professional experience, namely exposure to viewing CSAIO.

Assessment of the potential health risks associated with the aluminium, arsenic, cadmium and lead content in selected fruits and vegetables grown in Jamaica.

Thirteen Jamaican-grown food crops - ackee (), banana (), cabbage (), carrot (), cassava (), coco (), dasheen (), Irish potato (), pumpkin (), sweet pepper (), sweet potato (), tomato () and turnip () - were analysed for aluminium, arsenic, cadmium and lead by atomic absorption spectrophotometry and instrumental neutron activation analysis. The fresh weight mean concentrations in these food crops (4.25-93.

Radiation and criticality safety analyses for the highly-enriched uranium core removal from a research reactor.

Analysis was performed to estimate radiation levels during removal and packaging of the highly-enriched uranium core of the JM-1 SLOWPOKE-2 research reactor. Due to severe limitations of space in and around the reactor pool, the core could not be removed in the conventional manner as was done for previous SLOWPOKE defuelling operations. A transfer shield, with a balance between shielding efficacy, volume and weight was designed.

Little evidence for intralocus sexual conflict over the optimal intake of nutrients for life span and reproduction in the black field cricket Teleogryllus commodus.

There is often large divergence in the effects of key nutrients on life span (LS) and reproduction in the sexes, yet nutrient intake is regulated in the same way in males and females given dietary choice. This suggests that the sexes are constrained from feeding to their sex-specific nutritional optima for these traits. Here, we examine the potential for intralocus sexual conflict (IASC) over optimal protein and carbohydrate intake for LS and reproduction to constrain the evolution of sex-specific nutrient regulation in the field cricket, Teleogryllus commodus.

Enacting Firm, Fair and Friendly Practice: A Model for Strengths-Based Child Protection Relationships?

Strengths-based solution-focused approaches are gaining ground in statutory child protection work, but few studies have asked front line practitioners how they navigate the complex worker-client relationships such approaches require. This paper describes one component of a mixed-methods study in a large Canadian statutory child protection agency in which 225 workers described how they applied the ideas of strengths-based practice in their daily work. Interviews with twenty-four practitioners were analysed using an interpretive description approach.

MCAST: scanning for cis-regulatory motif clusters.

Unlabelled: Precise regulatory control of genes, particularly in eukaryotes, frequently requires the joint action of multiple sequence-specific transcription factors. A cis-regulatory module (CRM) is a genomic locus that is responsible for gene regulation and that contains multiple transcription factor binding sites in close proximity. Given a collection of known transcription factor binding motifs, many bioinformatics methods have been proposed over the past 15 years for identifying within a genomic sequence candidate CRMs consisting of clusters of those motifs.

The MEME Suite.

The MEME Suite is a powerful, integrated set of web-based tools for studying sequence motifs in proteins, DNA and RNA. Such motifs encode many biological functions, and their detection and characterization is important in the study of molecular interactions in the cell, including the regulation of gene expression. Since the previous description of the MEME Suite in the 2009 Nucleic Acids Research Web Server Issue, we have added six new tools.