Publications by authors named "Charles D McCane"
Article Synopsis
- Socioeconomic deprivation negatively impacts functional outcomes after intracerebral hemorrhage (ICH), with stroke severity and cerebral small vessel disease (CSVD) both playing significant roles in these outcomes.
- The study analyzed data from 677 patients, examining the relationships between socioeconomic status, stroke severity, CSVD burden, and functional outcomes at 90 days post-ICH.
- Findings indicate that high deprivation, severe CSVD, and increasing stroke severity independently correlate with a higher likelihood of severe disability or death, underscoring the importance of these factors in patient outcomes.
Objective: The role of physician experience and patient volumes on the outcome of surgical or endovascular procedures has been well-studied but there are limited data on how these factors affect the outcome of medical therapy.
Methods: In the stenting and medical cohorts of the Stenting and Aggressive Medical Management for the Prevention of Recurrent Ischemic Stroke (SAMMPRIS) trial, we compared Kaplan-Meier (K-M) curves for the primary endpoint (any stroke or death within 30 days of enrollment or ischemic stroke in the territory beyond 30 days) using the log-rank test and the percentages of patients achieving target levels for primary and secondary risk factors during the study using Fisher exact test between patients at high-enrolling (≥12 patients) vs low-enrolling (<12 patients) sites.
Results: In the stenting group, the K-M curves for the primary endpoint were similar at high-enrolling sites and low-enrolling sites (p = 0.