A Mother-to-Child Transmission Study in Nigeria: The Impact of Maternal HIV Infection and HAART on Plasma Immunoglobulins, Cytokine Profiles and Infant Outcome.

Prevention of mother-to-child transmission (PMTCT) of HIV with highly active antiretroviral therapy (HARRT) allows the HIV pregnant mothers to have vaginal delivery and breastfeed. Here we investigated the maternal plasma immunoglobulin, cytokine secretion and the outcome of the exposed infants among the HIV HAART treated pregnant women in Nigeria. In this study, different plasma immunoglobulins and cytokines were measured in the HIV HAART treated pregnant mothers.

Antioxidant activity in HIV and malaria co-infected subjects in Anambra State, southeastern Nigeria.

Objective: To determine the antioxidant status of HIV and malaria co-infected participants.

Methods: Blood samples collected from the 193 randomly recruited participants were used for HIV screening, Plasmodium falciparum antigen screening, malaria parasite density count, CD4(+) T cell count, glutathione reductase, glutathione peroxidase and total antioxidant status measurement. Standard laboratory methods were used for the analysis.