Chest CT abnormalities and quality of life: relationship in adult cystic fibrosis.

Background: To evaluate the relationship between lung parenchymal abnormalities on chest CT and health-related quality of life in adult cystic fibrosis (CF).

Methods: The chest CT scans of 101 consecutive CF adults (mean age 27.8±7.

Tracheomalacia in adults with cystic fibrosis: determination of prevalence and severity with dynamic cine CT.

Purpose: To determine the prevalence and severity of tracheomalacia in adults with cystic fibrosis (CF) by using dynamic cine multidetector computed tomography (CT) and to correlate these findings with pulmonary function test (PFT) results and the severity of parenchymal lung disease.

Materials And Methods: In this institutional review board-approved HIPAA-compliant study, 40 patients with CF (22 men, 18 women; mean age, 28 years +/- 8 [standard deviation]; age range, 18-54 years) prospectively underwent PFTs, standard thin-section CT, and two dynamic cine multidetector CT acquisitions. Ten control subjects underwent dynamic cine multidetector CT.