Publications by authors named "Charles Ayogu"
Modulation of the Lipid Profile, Hepatic and Renal Antioxidant Activities, and Markers of Hepatic and Renal Dysfunctions in Alloxan-Induced Diabetic Rats by Virgin Coconut Oil.
Endocr Metab Immune Disord Drug Targets
March 2020
Article Synopsis
- Limited research exists on the effects of Virgin Coconut Oil (VCO) on diabetes in humans and animals.
- The study aimed to analyze the impact of VCO on various health indicators in diabetic rats, including lipid profiles and liver/kidney functions.
- Results indicated that while VCO did not significantly alter blood glucose or body weights, it positively influenced certain antioxidant activities and lipid markers in comparison to diabetic controls.
Article Synopsis
- The prevalence of type 2 diabetes mellitus (T2DM) is rising, highlighting the need for new treatment options with fewer side effects compared to current oral medications.
- Free fatty acid receptor 1 (FFAR1), which is activated by certain fatty acids and enhances insulin secretion, shows potential as a therapeutic target for T2DM.
- Recent advancements in the development of novel FFAR1 agonists are promising for improving the management of T2DM with fewer adverse effects.