Publications by authors named "Charles A Hay"
Introduction: Diagnosis of axial spondyloarthritis (axSpA) is frequently delayed for years after symptom onset. However, little is known about patient and healthcare professional (HCP) perspectives on barriers and facilitators in axSpA diagnosis. This study explored the experiences and perceptions of both groups regarding the factors affecting the timely diagnosis of axSpA.
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- - The study investigates the common issue of delays in diagnosing pediatric inflammatory bowel disease (IBD), focusing on the time taken from symptom onset to diagnosis, which varies across different studies.
- - A systematic review of medical literature identified 24 relevant studies, revealing that the median diagnostic delay ranges from 2 to 24 months, with children diagnosed with Crohn's Disease (CD) experiencing longer delays compared to those with ulcerative colitis (UC).
- - The findings indicate a significant wait for diagnosis in children, particularly for CD, and suggest that further research is needed to understand the impact of specific patient characteristics on these delays.
Article Synopsis
- Identification of axial spondyloarthritis (axSpA) often takes years, with median diagnostic delays ranging from 2 to 6 years, despite some improvements in recent decades.
- The study reviewed 69 articles to analyze the diagnostic delay and found that the delays reported were skewed, with some cases taking up to 8 years for a diagnosis.
- Only gender and family history of axSpA showed consistent associations with the diagnostic delay, but neither significantly impacted the length of time it takes for patients to be diagnosed.
Mortality in Patients With Gout Treated With Allopurinol: A Systematic Review and Meta-Analysis.
Arthritis Care Res (Hoboken)
July 2021
Article Synopsis
- The objective of the systematic review and meta-analysis was to evaluate the long-term effects of allopurinol, a medication for gout, on mortality rates.
- Researchers searched multiple databases for studies examining the relationship between allopurinol use and cardiovascular or all-cause mortality in gout patients.
- Results showed no significant association between allopurinol and all-cause mortality, but the limited number of studies suggests the need for further research in this area.
Background: Though gout is more prevalent in men than women, it remains unclear whether gender influences risk factors for incident gout. We aimed to systematically review all cohort studies examining risk factors for the development of gout by gender.
Methods: MEDLINE, EMBASE, CINAHL and the Cochrane Library were searched from inception to March 2019.
Polymyalgia rheumatica and giant cell arteritis are relatively common, but under research inflammatory rheumatological conditions. This survey aimed to ascertain the matters in which patients feel they need support with these conditions and appraise how the Charity PMRGCAuk currently supports these needs and could do so in the future. PMRGCAuk members (n = 910) were invited to complete an on-line survey.
View Article and Find Full Text PDFBackground: Gout treatment remains suboptimal. Identifying populations at risk of developing gout may provide opportunities for prevention. Our aim was to assess the risk of incident gout associated with obesity, hypertension and diuretic use.
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