Publications by authors named "Charlene Kang"
Cell Signal
February 2007
Article Synopsis
- PKC delta and ShcA are involved in how cells respond to oxidative stress, particularly in the presence of hydrogen peroxide (H2O2).
- The study reveals that PKC delta interacts with ShcA and that this interaction is enhanced when H2O2 is present, causing them to move together in the cytoplasm.
- Phosphorylation of ShcA at Ser29 by activated PKC delta is essential for triggering ERK activation in response to oxidative stress, indicating that their relationship is crucial for cellular responses to H2O2.
