Antifungal Activity of Isolated Compounds from the Leaves of (Burch.) Sond. and (L.) Dunal against Pathogens.

Crop diseases caused by pathogens, among other microorganisms, threaten crop production in both commercial and smallholder farming. There are increasing concerns about the use of conventional synthetic fungicides due to fungal resistance and the associated negative effects of these chemicals on human health, livestock and the environment. This leads to the search for alternative fungicides from nature, especially from plants.

Comparative Characterization of Hsp70-1 Relative to DnaK Reveals the Functional Specificity of the Parasite Chaperone.

Hsp70 is a conserved molecular chaperone. How Hsp70 exhibits specialized functions across species remains to be understood. Hsp70-1 (PfHsp70-1) and DnaK are cytosol localized molecular chaperones that are important for the survival of these two organisms.