Publications by authors named "Charissa A Bloom"
Sex-based differences in candidacy for transcatheter tricuspid valve intervention.
Catheter Cardiovasc Interv
October 2024
Article Synopsis
- - Women have a higher prevalence of tricuspid regurgitation (TR) and tend to present with more advanced stages of the condition compared to men, leading to the exploration of sex-based differences in eligibility for transcatheter tricuspid valve interventions (TTVI).
- - A study of 569 patients revealed that while men exhibited more left ventricular dysfunction and heart failure signs, women were more likely to experience isolated TR and TR linked to severe pulmonary hypertension.
- - Despite differences in presenting conditions, the majority of patients were not eligible for TTVI, and sex did not significantly impact eligibility for the procedure.
We present a 19-year-old male athlete, without cardiovascular risk factors, with anterior ST-segment elevation myocardial infarction caused by left anterior descending artery spontaneous coronary artery dissection. Symptoms began during a swim practice, and patient endorsed using C4 Ripped (Cellucor), a preworkout supplement to enhance athletic performance. We hypothesize that this was the major contributor to presentation.
View Article and Find Full Text PDFThe etiology of schizophrenia (SCZ) is multifactorial, and depending on a host of genetic and environmental factors. Two putative SCZ susceptibility genes, Disrupted-in-Schizophrenia-1 (DISC1) and reelin (RELN), interact at a molecular level, suggesting that combined disruption of both may lead to an intensified SCZ phenotype. To examine this gene-gene interaction, we produced a double mutant mouse line.
View Article and Find Full Text PDF