Anterior cruciate ligament (ACL) deficient and reconstructed knees display altered biomechanics during gait. Identifying significant gait changes is important for understanding normal and ACL function and is typically performed by statistical approaches. This paper focuses on the development of an explainable machine learning (ML) empowered methodology to: (i) identify important gait kinematic, kinetic parameters and quantify their contribution in the diagnosis of ACL injury and (ii) investigate the differences in sagittal plane kinematics and kinetics of the gait cycle between ACL deficient, ACL reconstructed and healthy individuals.
View Article and Find Full Text PDFwas initially included as an author in the original publication [...
View Article and Find Full Text PDFKnee Osteoarthritis (ΚΟΑ) is a degenerative joint disease of the knee that results from the progressive loss of cartilage. Due to KOA's multifactorial nature and the poor understanding of its pathophysiology, there is a need for reliable tools that will reduce diagnostic errors made by clinicians. The existence of public databases has facilitated the advent of advanced analytics in KOA research however the heterogeneity of the available data along with the observed high feature dimensionality make this diagnosis task difficult.
View Article and Find Full Text PDFThe global spread of COVID-19 led the World Health Organization to declare a pandemic on 11 March 2020. To decelerate this spread, countries have taken strict measures that have affected the lifestyles and economies. Various studies have focused on the identification of COVID-19's impact on the mental health of children and adolescents via traditional statistical approaches.
View Article and Find Full Text PDFGlobal competition among businesses imposes a more effective and low-cost supply chain allowing firms to provide products at a desired quality, quantity, and time, with lower production costs. The latter include holding cost, ordering cost, and backorder cost. Backorder occurs when a product is temporarily unavailable or out of stock and the customer places an order for future production and shipment.
View Article and Find Full Text PDFObjective: Feature selection (FS) is a crucial and at the same time challenging processing step that aims to reduce the dimensionality of complex classification or regression problems. Various techniques have been proposed in the literature to address this challenge with emphasis to medical applications. However, each one of the existing FS algorithms come with its own advantages and disadvantages introducing a certain level of bias.
View Article and Find Full Text PDFOsteoarthritis is a joint disease that commonly occurs in the knee (KOA). The continuous increase in medical data regarding KOA has triggered researchers to incorporate artificial intelligence analytics for KOA prognosis or treatment. In this study, two approaches are presented to predict the progression of knee joint space narrowing (JSN) in each knee and in both knees combined.
View Article and Find Full Text PDFBone metastasis is among the most frequent in diseases to patients suffering from metastatic cancer, such as breast or prostate cancer. A popular diagnostic method is bone scintigraphy where the whole body of the patient is scanned. However, hot spots that are presented in the scanned image can be misleading, making the accurate and reliable diagnosis of bone metastasis a challenge.
View Article and Find Full Text PDF