Patterns of nonsyndromic tooth agenesis and sexual dimorphism.

Background: Sex dimorphism has been implicated in oral health differences and the pathogenesis of oral diseases, such as tooth agenesis, periodontal disease, dental caries, and tooth loss. Tooth agenesis (TA) is one of the most common developmental anomalies in humans, and its prevalence and patterns are different across ethnic groups. The aim of this study was to investigate the phenotypes and sex-associated patterns of nonsyndromic tooth agenesis (TA) in Thai dental patients.

Phenotypic and Genotypic Features of Thai Patients With Nonsyndromic Tooth Agenesis and Variants.

Tooth agenesis is one of the most common orodental anomalies that demonstrate phenotypic and genotypic heterogeneity with a prevalence of 2.5%-7%. Mutations in have been proposed to be the most common cause of nonsyndromic tooth agenesis (NSTA).