Introducing Cytology-Based Theranostics in Oral Squamous Cell Carcinoma: A Pilot Program.

We aimed to evaluate the feasibility and reliability of brush cytology in the biomarker expression profiling of oral squamous cell carcinomas within the concept of theranostics, and to correlate this biomarker profile with patient measurable outcomes. Markers representative of prognostic gene expression changes in oral squamous cell carcinoma was selected. These markers were also selected to involve pathways for which commercially available or investigational agents exist for clinical application.

Malignant Leydig-cell tumor of the testis diagnosed by fine-needle aspiration using ThinPrep technique.

Leydig cell tumors (LCT) are rare sex cord-stromal tumors that account for 2-3% of all testicular tumors. Approximately 10% of LCTs shows evidence of malignant behavior. We present a case of LCT with severe atypia diagnosed by fine-needle aspiration (FNA) in a 49-year-old man who presented with gynecomastia and right testis enlargement.

A rare case of paratesticular embryonal rhabdomyosarcoma diagnosed by fine needle aspiration: a case report.

Background: Rhabdomyosarcoma is the most common soft tissue sarcoma of children < 15 years of age.

Case: We report a case of a paratesticular rhabdomyosarcoma diagnosed by fine needle aspiration (FNA) in an 18-year-old man with enlargement of the right testis. The FNA material revealed mainly isolated small to median-sized malignant cells with various shapes.