[The clinical and prognostic information value of painless myocardial ischemia in the early postinfarct period].

A study was made of painless myocardial ischemia in the early postinfarction period (day 14) in order to define its influence on the clinical course and immediate prognosis. 25 patients aged 32 to 60 years with acute primary myocardial infarction were examined. 17 patients had large-focal and 8 small-focal infarction.

[Diagnosis of dilated cardiomyopathy using patient blood serum and myocardial tissue culture].

Based on a study of the interaction of the sera from healthy persons (20), patients with coronary disease (20), rheumatic heart disease (20), myocarditis (20), congestive dilated cardiomyopathy (48) it was established that the sera from dilated cardiomyopathy patients exert an inhibitory effect on the contraction of chick embryo myocardial explants in experiments in vitro. Three grades of the inhibitory effect were detected, depending on the patient's status gravity. The sera from healthy persons and patients with the enumerated cardiovascular diseases failed to produce such an effect.

[Clinical significance of reciprocal changes in the ECG in acute myocardial infarction].

A total of 206 patients with acute myocardial infarction marked by infarction localization in the anterior and inferior walls were examined. It is revealed that reciprocal changes, namely the depression of the ST segment are of prognostic significance in the assessment of the clinical course of the disease, with the ST depression being recorded for over one day. The patients demonstrated a reduction in left ventricle (LV) function, namely a decrease in the ejection fraction of the LV.

Left ventricular contractility related to the state of the coronary bed.

The authors studied total and segmental contractility of the left ventricular (LV) myocardium in patients with acute myocardial infarction with single and multiple coronary artery (CA) disease. The group included 75 patients with acute transmural myocardial infarction; coronary arteriography was performed in 56 of them. All patients underwent echocardiography (sector scanning), on the basis of which total (ejection fraction) and segmental parameters (segmental ejection fraction, fraction of segmental wall shortening, velocity of change of segmental area, velocity of change in segmental wall thickness) of LV contractility were calculated.

[Changes in intracardiac blood flow in the acute period of myocardial infarction (according to the results of 2-dimensional impulse Doppler echocardiography].

Quantitative parameters of intracardiac blood flow were examined by impulse dopplerography in normal subjects and patients with acute transmural myocardial infarction with reference to the severity of disturbance of left-ventricular segmental contractility. The flow rate through the apical region and left-ventricular efferent tract was basically similar in normal subjects and coronary patients without myocardial infarction. Where myocardial segmental contractility was disturbed, changes in flow rate are different at different left-ventricular levels and depend on the site of infarction, the extent of left-ventricular involvement and the condition of intact myocardium.

[Determination of pulmonary capillary wedge pressure by the sectoral scanning method].

Eighty-seven cases of acute myocardial infarction were examined by sectoral scanning to assess the contractility of all heart chambers. The data, particularly the occlusion pressure of pulmonary capillaries, were compared with those obtained at catheterization of the right compartments of the heart. Mathematical formulas were derived to enable the identification of patients with increased occlusion pressure and quantify its magnitude on the basis of noninvasive echocardiographic studies.

[Function of the heart chambers in acute myocardial infarct].

A study of 87 patients, admitted to hospital within the first day of acute myocardial infarction (AMI) identified 3 groups of patients on the basis of their pulmonary capillary occlusion pressure (OP) values. Sixteen normal subjects made up the control group. Myocardial contractility and volume characteristics obtained by sectoral scanning were reviewed.

[Potentials of noninvasive methods in diagnosing multiple coronary artery lesions in ischemic heart disease].

A total of 111 patients, aged 35 to 60, were examined. Of those, 97 had survived transmural or large-focal myocardial infarction (MI) 1-2 years before the study. The patients were divided into groups according to MI localization and the number of affected coronary arteries.

[Determining the area of myocardial damage by the method of sectorial scanning and its value for prognosis of the outcome of acute myocardial infarction].

The authors describe a method for measuring the myocardial injury area, and show the prognostic value of the latter based on examination of 100 patients admitted to the Cardioresuscitation Department with a diagnosis of acute transmural or large-focal myocardial infarction. The lifetime evaluation data of the IM size by means of two-dimensional echocardiography were in a good agreement (r = 0.85) with the morbid anatomy data.

[Role of certain factors in thrombus formation in patients with myocardial infarct complicated by an acute aneurysm].

A total of 240 patients with acute myocardial infarction (MI) were examined over time with the use of two-dimensional echocardiography. The influence of such factors as the scope of involvement of the left ventricle myocardium, changes of its contractility and hemostasis on thrombus formation in the left ventricle was investigated. It was established that thrombus is formed primarily during anterior myocardial infarction with an extensive injury to the apical segment--formation of a large aneurysm.

[Diagnosis of impairment of segmental myocardial contractility during the acute phase of infarction using sector scanning].

The paper is concerned with sector scanning for early diagnosis of acute myocardial infarction. A total of 157 patients were examined within the first 2 to 6 hours after transmural infarction. The segments of the left ventricle which are mostly affected in infarctions of different sites were defined.

[Elevation of the ST segment during physical exertion: computer analysis, comparison with angiographic data; clinical significance].

A total of 41 male patients responding with ST elevation to treadmill exercise were investigated using coronaro- and ventriculography, and sector-scanning echocardiography. All the patients had a history of anterior myocardial infarction. Computer analysis of changes in ST interval showed ST incline and integral to be the most informative parameters.

[Assessment of myocardial contractility by the sector scanning of myocardial infarct patients].

A comparative assessment of left-ventricular myocardial contractility in patients with myocardial infarction was made using sector scanning and ventriculographic techniques. Eight patients were investigated within 2-4 hours of the infarction, and twenty patients, on days 20-25 of the disease. Ultimate diastolic, ultimate systolic and stroke volumes were calculated, as was the expulsion fraction, using the mono- and biplane method and modified formula 5/6 AL.