Encapsulation of Ibuprofen by Pickering-Stabilized Antibubbles.

Ibuprofen, one of the most widely used nonsteroidal anti-inflammatory drugs, is a poor-tasting and poorly soluble drug. As an alternative approach to overcome these issues, ibuprofen was encapsulated in Pickering antibubbles using two different oils, cyclomethicone and cyclooctane, as processing aids. The amount of the loaded active agent was determined by thermogravimetry (TG), while the analysis of the evolved gases, performed by online coupling of the heating device to an infrared and a mass spectrometer (EGA-FTIR-MS), allowed for describing the drug decomposition mechanism.

Transition of Liquid Drops on Microstructured Hygrophobic Surfaces from the Impaled Wenzel State to the "Fakir" Cassie-Baxter State.

Low adhesion of liquids on solid surfaces can be achieved with protrusions that minimize the contact area between the liquid and the solid. The wetting state where an air cushion forms under the drop is known as the Cassie-Baxter state. Surfaces where liquids form macroscopic contact angles above 150° are called superhydrophobic and superhygrophobic, if we refer to water or any liquid, respectively.