Publications by authors named "Charalampos Kypraios"

Objectives: In this prospective study, we investigated the correlation between prostate-specific antigen (PSA) levels in the blood of patients with prostate cancer in biochemical recurrence after radical treatment with the semiquantitative parameters standard uptake value maximum (SUV max ) and the total metabolic tumor volume (TMTV) in the metastatic foci depicted in 18F-prostate-specific membrane antigen (PSMA)-1007 and 18F-choline PET/computed tomography (CT) imaging.

Methods: We prospectively examined 104 patients with biochemical relapse of prostate cancer after primary definitive treatment. All patients underwent one 18F-PSMA-1007 and one 18F-choline PET/CT examination in randomized order within a time frame of 10 days and were followed for at least 6 months (182 ± 10 days).

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Article Synopsis
  • The study compared the effectiveness of 18F-PSMA-1007 (PSMA) and 18F-Choline PET/CT (FCH) in detecting prostate cancer recurrence in 186 patients who had previously received treatment.
  • Findings revealed that PSMA had a significantly higher detection rate (84%) compared to FCH (69%), along with greater sensitivity, making it the more reliable option for diagnosing biochemically recurrent prostate cancer.
  • The research concluded that PSMA is superior to FCH in identifying metastatic lesions, especially at lower PSA levels, enhancing diagnostic accuracy in prostate cancer patients experiencing recurrence.
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Iatrogenic ureteral injuries are a significant complication during pelvic surgery, requiring a multidisciplinary approach for optimal repair. When a ureteral injury is suspected postoperatively, abdominal imaging is essential to determine the type of injury and thus the timing and method of reconstruction. That can be performed either by a CT pyelogram or by an ureterography-cystography with or without ureter stenting.

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