Publications by authors named "Chappuy H"

Background And Importance: Access to healthcare remains a persistent challenge. Socially disadvantaged populations often encounter barriers to care and may frequently seek out emergency departments (EDs), including for nonurgent medical care.

Objective: The objective of this study is to study the association between nonurgent presentations to pediatric EDs and patients' socioeconomic environment in an urban setting.

View Article and Find Full Text PDF
Article Synopsis
  • In the EU, cocaine availability has risen, with increased purity, leading to a significant rise in pediatric cocaine toxicity cases, particularly in children under 6.
  • A study over 11 years showed an eightfold increase in admissions for cocaine intoxication, with severe clinical symptoms, primarily neurologic and cardiovascular.
  • The findings highlight that as cocaine trends worsen, the health risks for children are escalating, marking a critical public health issue.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the characteristics and outcomes of pediatric patients hospitalized with COVID-19 in the Greater Paris area, revealing that children generally experience milder symptoms compared to adults.
  • A total of 9,163 children under 18 were analyzed from March 2020 to March 2022 across three waves of COVID-19 variants, with their cases categorized by severity into PIMS, symptomatic, and mild or asymptomatic infections.
  • Findings indicate an increase in hospitalizations over time, with the third wave showing the highest frequency of cases and a notable increase in respiratory complications among those admitted during this period.
View Article and Find Full Text PDF

Introduction: A strict lockdown was decided from 17/03/2020 to 11/05/2020 in France in order to tackle the first wave of the COVID19 pandemic. In the Great Paris region, several areas are severely affected by overcrowding, creating difficult conditions for children and their families during a period of nearly two months. The objective was to assess the effects of the 2020 spring lockdown on injuries, child abuse and neglect.

View Article and Find Full Text PDF

Since the beginning of the COVID-19 pandemic, other respiratory illnesses decreased worldwide. This study described the consequences of public health measures on respiratory syncytial virus (RSV) severe infections in France, where an interseasonal resurgence of RSV occurred recently. All patients admitted to Necker Hospital (Paris) between August 2018 and April 2021 with a diagnosis of RSV-associated acute lung respiratory infection (ALRI) were enrolled.

View Article and Find Full Text PDF

Emergency departments (EDs) have a key role in the public health system. They are facing a constant growth of their volume. Forecasting the daily volume is a major tool to adapt the allocation of resources.

View Article and Find Full Text PDF

Purpose: Registered nurses must have a level of scientific literacy to be able to interpret research data and access Scientific's knowledge. Several studies have been conducted to explore barriers and levers to the dissemination of nurse's knowledge; however, the scientific literacy that nursing students acquire has not been studied.

Objective: The aim was to examine and compare the way that research is taught to undergraduate nursing students in France and other countries.

View Article and Find Full Text PDF

Objectives: The objective of this study was to examine the impact of study characteristics on the score of the pragmatism/explanatory continuum of randomized controlled trials (RCTs) published in nursing journals using the PRagmatic Explanatory Continuum Indicator Summary (PRECIS)-2 tool.

Study Design And Setting: RCTs concerning five themes of nursing care indexed in the PubMed and CINAHL databases published from 2002 to 2005 and 2012 to 2015 were selected by title/abstract. A sample of 400 was randomly selected and evaluated with the PRECIS-2 tool and reading grid.

View Article and Find Full Text PDF

Aim: To assess the prevalence of clinically urgent intracranial pathology (CUIP) in children visiting the emergency department with a complex febrile seizure (CFS).

Methods: Retrospective cohort review. We analysed the visits of patients for a CFS from January 2007 to December 2011 in seven paediatric emergency departments.

View Article and Find Full Text PDF

Objective: To analyse parents' and children's understanding of consent information and assess their decision-making process in paediatric oncology.

Design: Prospective observational study.

Settings: Eleven French paediatric oncology units.

View Article and Find Full Text PDF

Background: Nursing care should be based on scientific evidence. However, studies must be performed rigorously with accurate reporting for their findings to be applicable to practice. Since the body of scientific nursing literature is broad, the quality and validity of its findings should be regularly controlled and verified to ensure their application and their practical impact.

View Article and Find Full Text PDF

Unlabelled: This study evaluated the first interaction (FI) between parents and health care providers at the time of admission of a child in pediatric intensive care unit (PICU), and explored the extent to which parents understood the medical information. This prospective study took place in three French university-affiliated PICUs. Forty-two parents of 30 children were interviewed.

View Article and Find Full Text PDF

Objective: As the results from epidemiological studies about the impact of outdoor air pollution on asthma in children are heterogeneous, our objective was to investigate the association between asthma exacerbation in children and exposure to air pollutants.

Methods: A database of 1 264 585 paediatric visits during the 2010-2015 period to the emergency rooms from 20 emergency departments (EDs) of 'Assistance Publique Hôpitaux de Paris (APHP)', the largest hospital group in Europe, was used. A total of 47 107 visits were classified as asthma exacerbations.

View Article and Find Full Text PDF

Background: Reliably distinguishing bacterial from viral infections is often challenging, leading to antibiotic misuse. A novel assay that integrates measurements of blood-borne host-proteins (tumor necrosis factor-related apoptosis-inducing ligand, interferon γ-induced protein-10, and C-reactive protein [CRP]) was developed to assist in differentiation between bacterial and viral disease.

Methods: We performed double-blind, multicenter assay evaluation using serum remnants collected at 5 pediatric emergency departments and 2 wards from children ≥3 months to ≤18 years without ( = 68) and with ( = 529) suspicion of acute infection.

View Article and Find Full Text PDF

Study Objective: We assess the prevalences of bacterial meningitis and herpes simplex virus meningoencephalitis (HSV-ME) in children with a complex febrile seizure and determine these prevalences in the subgroup of children with a clinical examination result not suggestive of meningitis or encephalitis.

Methods: This multicenter retrospective study was conducted in 7 pediatric emergency departments (EDs) in the region of Paris, France. Visits of patients aged 6 months to 5 years for a complex febrile seizure from January 2007 to December 2011 were analyzed.

View Article and Find Full Text PDF

Pediatric intensive care units (PICUs), whose accessibility to parents raises controversy, often operate under their own rules. Patients are under critical and unstable conditions, often in a life-threatening situation. In this context, the communication with the parents and their participation in the unit may be difficult.

View Article and Find Full Text PDF
Article Synopsis
  • - Heelsticks are the most common invasive procedure in NICUs, but there's limited data on how often they're done and how pain is managed during the process.
  • - The study, EPIPPAIN 2, involved 562 newborns in 16 NICUs in Paris and found that on average, each baby underwent 16 heelsticks, with a significant portion performed without adequate preprocedural analgesia.
  • - Factors linked to the higher likelihood of avoiding preprocedural pain relief included being female, born at full term, having more severe health issues, and if parents were not present during the procedure.
View Article and Find Full Text PDF
Article Synopsis
  • Newborns in ICUs often undergo painful procedures like venipunctures, which can have long-term negative effects on their neurodevelopment; however, there is limited data on how frequently these procedures occur and how pain is managed.
  • The study aimed to analyze the frequency of venipunctures, their pain intensity, and pain management practices, while also identifying factors that contribute to inadequate pre-procedural analgesia and higher pain scores.
  • Researchers included 495 newborns, finding that on average, each infant underwent nearly four venipunctures, with over half of those studied being very preterm; many procedures did not utilize adequate pain relief despite significant pain scores reported.
View Article and Find Full Text PDF

Objectives: National and international guidelines are very heterogeneous about the necessity to perform a lumbar puncture (LP) in children under 12 months of age with a first simple febrile seizure. We estimated the risk of bacterial meningitis in children aged 6 to 11 months with a first simple febrile seizure.

Methods: This multicenter retrospective study was conducted in seven pediatric emergency departments (EDs) in the region of Paris, France.

View Article and Find Full Text PDF

Children suffer most from today's increasing precariousness. In France, access to care is available for all children through various structures and existing measures. The support for foreign children is overseen by specific legislation often unfamiliar to caregivers.

View Article and Find Full Text PDF

Introduction: Unscheduled visits (UV) are defined as visits to the family pediatrician (FP) without an appointment or when the appointment was made less than 24h before. Because the number of FPs has decreased since the 2000s, the FP might be less available for UVs and that might be one of the reasons for the increase in emergency department visits.

Objectives: The main objective of the study was to evaluate the proportion of UVs among visits with a FP.

View Article and Find Full Text PDF

Aims: To investigate 25-hydroxycholecalciferol [25(OH)D] population pharmacokinetics in children and adolescents, to establish factors that influence 25(OH)D pharmacokinetics and to assess different vitamin D3 dosing schemes to reach sufficient 25(OH)D concentrations (>30 ng ml(-1) ).

Methods: This monocentric prospective study included 91 young HIV-infected patients aged 3 to 24 years. Patients received a 100 000 IU vitamin D3 supplementation.

View Article and Find Full Text PDF

Background: There is no data on long-term benefit of once-a-day antiretroviral therapy (ART) with combination of DDI, 3TC and EFV to allow its use in future therapeutic strategies.

Objectives: To assess 24-month immuno-virological, adherence, tolerance, and effectiveness of a once-a-day ART with DDI, 3TC and EFV.

Methods: A phase 2 open trial including 51 children aged from 30 months to 15 years, monitored a once-a-day regimen for 24 months from 2006 to 2008 in the Departement de Pediatrie du CHUSS, at Bobo-Dioulasso in Burkina Faso.

View Article and Find Full Text PDF