Publications by authors named "Chapagain N"

Article Synopsis
  • - Achalasia cardia is a rare disorder affecting the lower esophageal sphincter, making it challenging to diagnose due to varying symptoms.
  • - The case series details three patients: an 18-year-old male and two females (37 and 47 years old) who faced different diagnostic experiences, from a prolonged journey to a quick diagnosis using barium swallow.
  • - All patients were successfully treated with laparoscopic Heller's myotomy and anterior Dor's fundoplication, emphasizing the need for early recognition and effective surgical options.
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  • Systemic lupus erythematosus (SLE) is an autoimmune condition affecting multiple organs, with rare cases involving concurrent IgA nephropathy, which complicates diagnosis and treatment.!* -
  • A 42-year-old woman with SLE presented symptoms such as limb swelling and bleeding issues, leading to a diagnosis of lupus nephritis alongside IgA nephropathy lesions, and despite treatment, she experienced further complications like skin ulcers and orbital cellulitis.!* -
  • The case illustrates the diagnostic difficulties in SLE, highlighting the need for careful monitoring and timely interventions, and suggests a potential link between SLE and IgA nephropathy, warranting further research into the complexities of autoimmune disease management.!*
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Unlabelled: Paraquat emerges as a formidable medical dilemma in Southeast Asia, its toxic effects attributed to the generation of free radicals and oxidative stress, with a specific predilection for diverse tissues, most notably the lungs. The scarcity of effective treatment modalities in resource-constrained settings magnifies the magnitude of the paraquat poisoning predicament. This report outlines the successful management of a 25-year-old man who ingested a lethal dose of paraquat.

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Unlabelled: Hepatitis B is a global acute and chronic life-threatening liver infection caused by the hepatitis B virus. During cadaveric dissection, clinical rotations, and autopsy posting, medical students get exposed to patients' blood and body fluids, which increases the risk of hepatitis B infection. Hepatitis B can be prevented by vaccines that are safe, easily available, and effective, however many medical students are still unvaccinated.

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Introduction: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Serum lactate is useful in predicting the prognosis of critically ill patients. Elevated blood lactate levels as well as delayed clearance have been linked to higher mortality in sepsis.

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Article Synopsis
  • * Symptoms include low blood pressure, fluid loss, and general discomfort like fatigue and nausea, often triggered by stress or inadequate steroid treatment.
  • * A case study of a 3-year-old boy shows that noncompliance with medication and gastroenteritis led to an adrenal crisis, managed through emergency treatment and lifelong hormone replacement therapy.
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Introduction: Acute organophosphorus pesticide poisoning is widespread and the most common in many developing countries, including Nepal. Through the inhibition of acetylcholinesterase, organophosphorus poisoning is characterised by the clinical picture of acute cholinergic crisis. Many researchers have shown increased levels of liver enzymes and decreased levels of serum cholinesterase in organophosphorus poisoning, however, very little work has been done in Nepal that studies the correlation between serum cholinesterase and liver enzymes in organophosphorus poisoning.

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Importance: In the United States, 16 million family caregivers provide long-term care for patients with dementia. Although one's physical, mental, and cognitive health depends on sleep, many caregivers experience chronic stress, and stress is typically associated with worse sleep quantity and quality.

Objective: To quantify the extent, nature, and treatability of sleep problems in dementia caregivers.

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Health care costs, and those for inpatient care in particular, pose a barrier to seeking health care, and cost be a major cause of indebtedness and impoverishment, particularly among the poor. The Ministry of Health in Nepal intends to initiate alternative financing schemes such as community and social health insurance schemes as a means to supplement the government health sector financing source. Social Health Insurance (SHI) is a mechanism for financing and purchasing / delivering health care to workers in the formal sector regulated by the government.

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