Publications by authors named "Chaoyun Yuan"
Mechanisms underlying delirium in patients with critical illness.
Front Aging Neurosci
September 2024
Article Synopsis
- Delirium is an acute cognitive disorder, often seen in critically ill patients, characterized by disturbances in attention and awareness, with symptoms that can fluctuate.
- It can lead to serious complications such as unplanned extubation, longer hospital stays, increased risk of infections, cognitive impairments, and even mortality.
- The paper reviews the causes of delirium to improve understanding and create effective prevention and treatment strategies for critically ill patients.
What Is Known And Objective: Patients with kidney disease receiving immunosuppressive drugs (ISDs) (tacrolimus, cyclosporine and glucocorticoids) have a high risk of developing new-onset diabetes mellitus (NODM). We aimed to establish a precise and convenient model for predicting NODM in patients receiving immunosuppressive drugs.
Methods: This retrospective study recruited 1883 patients receiving ISDs between January 2010 and October 2018.
5-Methoxytryptophan (5-MTP) is a tryptophan metabolite with recently discovered anti-inflammatory and tumor-suppressing activities. Its synthesis is catalyzed by a hydroxyindole -methyltransferase (HIOMT)-like enzyme. However, the exact identity of this HIOMT in human cells remains unclear.
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