Synopsis of recent research by authors named "Chaoyun Pan"
- Chaoyun Pan's recent research focuses on the metabolic reprogramming of cancer cells, particularly how fatty acid oxidation and amino acid catabolism influence tumor metastasis and chemotherapy sensitivity in various types of cancers, including cervical and ovarian cancers.
- Significant findings from Pan's studies highlight that increased fatty acid oxidation supports lymph node metastasis in cervical cancer, while suppression of translesion DNA synthesis via tyrosine catabolism enhances the effectiveness of chemotherapy in epithelial ovarian cancer.
- Additionally, Pan's work emphasizes the role of specific mitochondrial factors, like succinyl-CoA ligase ADP-forming subunit beta, in promoting cancer metastasis, indicative of the complex interplay between cellular metabolism and cancer progression.*
