Can signal delay and advertising lead to profit? A study on sporting.

Introduction: Live sporting event streaming (LSES) is becoming popular not only among consumers but also among sponsors. At the same time, influenced by China's convenient mobile terminals, the paid membership system for live broadcasting has also attracted the attention of marketers and scholars. To promote financial sustainability, we analyzed the internal mechanism of profitability in LSES based on stimulus-organism-response (SOR) theory and two-sided market characteristics.

Combination of apatinib mesylate and second-line chemotherapy for treating gastroesophageal junction adenocarcinoma.

Objective: To investigate the safety and efficacy of acitinib mesylate combined with chemotherapy in the treatment of patients with gastroesophageal junction adenocarcinoma.

Methods: A total of 119 patients with gastroesophageal junction adenocarcinoma were enrolled and randomized into an experimental group (n = 60) and a control group (n = 59). Both groups were treated with a combination of taxane, irinotecan and fluorouracil, while the experimental group also received acitinib mesylate.