Publications by authors named "Chaoyue Diao"
Article Synopsis
- This study investigates the possible causal link between gut microbiome and psoriatic arthritis (PsA) using advanced statistical techniques to analyze genetic data from large consortia.* -
- The researchers found that certain gut bacteria could reduce the risk of PsA, while others may increase it, indicating complex interactions between the gut microbiome and PsA.* -
- The analysis showed no significant reverse effect of PsA on gut microbiome composition, suggesting that gut bacteria may be more influential in the development of PsA than vice versa.*
Ras homolog gene family member A (RhoA) plays a major role in the Wnt/planar cell polarity (PCP) pathway, which is significantly activated in patients with rheumatoid arthritis (RA). The function of RhoA in RA synovitis and bone erosion is still elusive. Here, we not only explored the impact of RhoA on the proliferation and invasion of RA fibroblast-like synoviocytes (FLSs) but also elucidated its effect on mouse osteoclast and a mouse model of collagen-induced arthritis (CIA).
View Article and Find Full Text PDFBackground: DNA-damaging agents, including radiation and platinum-based chemotherapy, are indispensable treatments for non-small cell lung cancer (NSCLC) patients. However, cancer cells tend to be resistant to both radiation and chemotherapy, thus resulting in treatment failure or recurrence. The purpose of this study was to explore the effect and mechanism of long non-coding RNA (lncRNA) PANDAR (promoter of CDKN1A antisense DNA damage-activated RNA) on NSCLC sensitivity to radiation and chemotherapy.
View Article and Find Full Text PDFObjectives: The clinical heterogeneity of the progression of rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is high, and there is a lack of consensus on the clinical relevance and medical protocols. The purpose of this study is to explore the impact of clinical characteristics, new biomarkers and treatment options on the prognosis of RA-ILD patients and to explore whether these factors can predict the progression and death of these patients.
Methods: We retrospectively collected case data on RA-ILD patients who visited or were admitted to Changhai Hospital between October 2010 and September 2021.