Publications by authors named "Chaoyin Zhang"
Background: Epstein-Barr virus (EBV) infection is a major global threat; its manifestations range from the absence of symptoms to multiorgan malignancies and various gastrointestinal diseases. Analyzing the composition and metabolomic profile of gut microbiota during acute EBV infection might be instrumental in understanding and controlling EBV.
Methods: Six tree shrews were inoculated with EBV by intravenous injection.
Article Synopsis
- The study focused on hydroa vacciniforme-like lymphoproliferative disorder (HVLPD), examining clinical features, laboratory markers, treatment options, and factors linked to poor prognosis.
- Seven patients were analyzed, with findings showing papulovesicular lesions, systemic symptoms in some, and significant pathological indicators, including lymphocyte infiltration and elevated plasma EBV DNA.
- Key markers such as high levels of IgE, IFN-γ, TNF-α, and TCR gene rearrangements were associated with a poor prognosis, with three patients ultimately passing away despite quick recovery of skin lesions from treatment.
In this study, the physiological values of volumes of plasma, cells, total blood and the F blood factors were identified in 24 adult tree shrews (Tupaia belangeri; 12 male and 12 female; average BW of 123.9±19.19 g).
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