Foliar application of 24-epibrassinolide enhances leaf nicotine content under low temperature conditions during the mature stage of flue-cured tobacco by regulating cold stress tolerance.

Background: Low temperatures disrupt nitrogen metabolism in tobacco, resulting in lower nicotine content in the leaves. 24-epibrassinolide (EBR) is a widely used plant growth regulator known for its roles in enhancing cold tolerance and nitrogen metabolism. Nevertheless, it remains unclear whether EBR enhances leaf nicotine content under low temperature conditions during the mature stage of flue-cured tobacco.

Anticancer effects of OSW-1 on colorectal cancer cells via the ROS/NLRP3/Caspase-1 pyroptosis signaling pathway.

Pyroptosis, a form of programmed cell death, has recently emerged as a compelling molecular mechanism associated with the efficacy of chemotherapeutic drugs in tumor treatment. OSW-1, derived from the bulbs of Ornithogalum saundersiae Baker, exhibits a diverse range of pharmacological effects. However, its specific antitumor effects on colorectal cancer (CRC) and the mechanisms underlying these effects remain elusive.

Efficacy of internet-delivered universal and tailored transdiagnostic interventions for anxiety and depression: A systematic review and meta-analysis of randomized controlled trials.

Background: Internet-delivered transdiagnostic psychological interventions are promising approaches for the treatment of anxiety and depression. This study aimed to review and synthesize evidence related to the effectiveness of Internet-based transdiagnostic interventions for reducing anxiety and depression, and to compare the effects of universal versus tailored interventions.

Methods: A Systematic review search was conducted on the PubMed, EMBASE, Cochrane Library, Web of Science, PsychINFO, Medline, and CINAHL databases as of 28 March 2024.

Bird Species Detection Net: Bird Species Detection Based on the Extraction of Local Details and Global Information Using a Dual-Feature Mixer.

Bird species detection is critical for applications such as the analysis of bird population dynamics and species diversity. However, this task remains challenging due to local structural similarities and class imbalances among bird species. Currently, most deep learning algorithms focus on designing local feature extraction modules while ignoring the importance of global information.

Effectiveness of information technology-based cognitive behavioral therapy on depression and anxiety symptoms among older adults: Systematic review and meta-analysis.

Background: Depression and anxiety are prevalent among older adults. However, most older adults have poor access to age-specific mental health services. While Information technology-based Cognitive Behavioral Therapy (ICBT) has shown promise as an accessible alternative to face-to-face interventions, its effectiveness specifically within the older adults warrants further investigation.

Effect of group impromptu music therapy on improving test anxiety and emotional regulation ability in medical students.

Introduction: Test anxiety, a prevalent psychological issue among medical students, can profoundly impact their social, behavioral, and emotional development. This condition is significantly associated with challenges in emotional regulation, and to date, no effective clinical treatment has been established to address it. This study aimed to investigate the potential benefits and effects of group impromptu music therapy (GIMT) on enhancing emotional regulation skills and alleviating test anxiety in medical students.

Cuproptosis and Serine Metabolism Blockade Triggered by Copper-Based Prussian Blue Nanomedicine for Enhanced Tumor Therapy.

Cuproptosis, a newly defined cell death process, represents a novel modality with significant therapeutic potential in cancer treatment. Nevertheless, the modest concentration and transient half-life of copper ions in the bloodstream constrain their efficient delivery into tumor cells. In this study, a copper-based prussian blue nanostructure loaded with serine metabolic inhibitor (NCT-503@Cu-HMPB) is constructed for selectively inducing cuproptosis combined with disrupting serine metabolism.

Highly accurate absolute optical transfer delay measurement over a long distance assisted by the pulse time signal.

In this paper, an absolute optical transfer delay measurement method based on pulse time signal, pseudo-random code phase, and microwave phase is proposed. By employing two-stage integer ambiguity resolution, not only can a measurement range of several hundred kilometers be achieved, but sub-picosecond level measurement accuracy can also be attained. A test system was built in the laboratory and experimentally verified on a fiber optic link.

How to improve public environmental health by facilitating metro usage on weekend: exploring the non-linear and threshold impacts of the built environment.

Introduction: The accelerated motorization has brought a series of environmental concerns and damaged public environmental health by causing severe air and noise pollution. The advocate of urban rail transit system such as metro is effective to reduce the private car dependence and alleviate associated environmental outcomes. Meanwhile, the increased metro usage can also benefit public and individual health by facilitating physical activities such as walking or cycling to the metro station.

Multi-band enhanced nonreciprocal thermal radiation based on Weyl semimetals.

Previous studies manifested that the majority of structures that exhibit nonreciprocal thermal radiation in the mid-infrared are capable of achieving either single-band strong nonreciprocity or multi-band weak nonreciprocity at a large incidence angle. However, few structures can realize multi-band strong nonreciprocity at a small incidence angle. To address such scientific issues, we propose a tunable nonreciprocal thermal emitter based on gallium arsenide (GaAs)/graphene/Weyl semimetal (WSM).

The effects of tele-based interventions for depression and anxiety symptoms in patients with Chronic Obstructive Pulmonary Disease (COPD): A systematic review and meta-analysis.

Background: Depression and anxiety are common psychiatric symptoms in patients with Chronic Obstructive Pulmonary Disease (COPD). While face-to-face psychotherapy is a common option, tele-based interventions provide a more accessible alternative. However, a comprehensive synthesis of evidence from clinical trials for COPD patients has yet to be conducted.

8-weeks aerobic exercise ameliorates cognitive deficit and mitigates ferroptosis triggered by iron overload in the prefrontal cortex of / mice through Xc/GPx4 pathway.

Background: Alzheimer's disease (AD) is a degenerative disorder of the central nervous system characterized by notable pathological features such as neurofibrillary tangles and amyloid beta deposition. Additionally, the significant iron accumulation in the brain is another important pathological hallmark of AD. Exercise can play a positive role in ameliorating AD, but the mechanism is unclear.

Effectiveness of digital intelligence interventions on depression and anxiety in older adults: A systematic review and meta-analysis.

Background: Depression and anxiety are common mental disorders in later life. Digital intelligence interventions overcome the limitations of conventional psychotherapy and offer new treatments for depression and anxiety. However, the effectiveness among older adults remains unclear.

The chain mediating role of rumination and social withdrawal in the relationship between smartphone distraction and depression among Chinese nursing students.

Smartphone distraction (SD) is closely related to depression, and the prevalence of SD among nursing students is gradually increasing. However, the potential mechanism of the effect of SD on nursing students' depression is unclear. A total of 574 nursing students were assessed using Smartphone Distraction Scale, Ruminative Response Scale, Hikikomori Questionnaire, and Patient Health Questionnaire-9.

Precise measurement of chiral spectrum in the ultraviolet band using weak measurement and a deep neural network model.

Circular dichroism (CD) spectrum and optical rotation (OR) spectrum, crucial for understanding molecular properties and configurations, present challenges due to limited testing methods and equipment accuracy in the ultraviolet (UV) region. This study proposes a weak measurement system for chiral signals in varying concentrations in the ultraviolet range, optimized using a deep neural network (DNN) model. Introducing different post-selections to detect the circular dichroism spectrum and optical rotation spectrum separately, with contrast as a probe, it achieves a detection resolution of up to 10 rad.

Association between the triglyceride-glucose (TyG) index and stroke risk in Chinese normal-weight adults: a population-based study.

Background: Identifying high-risk populations and promoting stroke prevention measures can be achieved through studies on stroke and its risk factors. As a new alternative indicator of insulin resistance (IR), the triglyceride glucose (TyG) index may potentially increase stroke risk. However, the evidence confirming this association is inadequate and inconsistent, possibly due to variations in stroke assessment criteria or characteristics of the study populations.

Post-Quantum Secure Identity-Based Signature Scheme with Lattice Assumption for Internet of Things Networks.

The Internet of Things (IoT) plays an essential role in people's daily lives, such as healthcare, home, traffic, industry, and so on. With the increase in IoT devices, there emerge many security issues of data loss, privacy leakage, and information temper in IoT network applications. Even with the development of quantum computing, most current information systems are weak to quantum attacks with traditional cryptographic algorithms.

Forward-backward wavefront manipulation of orthogonal linearly polarized waves based on a metasurface zone plate.

Metasurface zone plates exhibit stronger optical control capabilities than traditional Fresnel zone plates, especially in polarization transformation and multiplexing. However, there are still few studies on metasurface zone plates that can be used for simultaneous control of forward and backward waves. In this work, we propose what is to our knowledge a new scheme that utilizes metasurface zone plates for orthogonal linear polarization separation and wavefront manipulation at the same time.

Exploring amyotrophic lateral sclerosis patients' experiences of psychological distress during the disease course in China: a qualitative study.

Objective: This study aims to explore the psychological distress course of Chinese amyotrophic lateral sclerosis (ALS) patients after the onset of the disease and to provide targeted nursing guidance.

Design: The interview content was analysed qualitatively. We used seven steps of Colaizzi's method to analyse the participants' data.