Background: Depression and anxiety are prevalent among older adults. However, most older adults have poor access to age-specific mental health services. While Information technology-based Cognitive Behavioral Therapy (ICBT) has shown promise as an accessible alternative to face-to-face interventions, its effectiveness specifically within the older adults warrants further investigation.
View Article and Find Full Text PDFIntroduction: Test anxiety, a prevalent psychological issue among medical students, can profoundly impact their social, behavioral, and emotional development. This condition is significantly associated with challenges in emotional regulation, and to date, no effective clinical treatment has been established to address it. This study aimed to investigate the potential benefits and effects of group impromptu music therapy (GIMT) on enhancing emotional regulation skills and alleviating test anxiety in medical students.
View Article and Find Full Text PDFCuproptosis, a newly defined cell death process, represents a novel modality with significant therapeutic potential in cancer treatment. Nevertheless, the modest concentration and transient half-life of copper ions in the bloodstream constrain their efficient delivery into tumor cells. In this study, a copper-based prussian blue nanostructure loaded with serine metabolic inhibitor (NCT-503@Cu-HMPB) is constructed for selectively inducing cuproptosis combined with disrupting serine metabolism.
View Article and Find Full Text PDFIn this paper, an absolute optical transfer delay measurement method based on pulse time signal, pseudo-random code phase, and microwave phase is proposed. By employing two-stage integer ambiguity resolution, not only can a measurement range of several hundred kilometers be achieved, but sub-picosecond level measurement accuracy can also be attained. A test system was built in the laboratory and experimentally verified on a fiber optic link.
View Article and Find Full Text PDFIntroduction: The accelerated motorization has brought a series of environmental concerns and damaged public environmental health by causing severe air and noise pollution. The advocate of urban rail transit system such as metro is effective to reduce the private car dependence and alleviate associated environmental outcomes. Meanwhile, the increased metro usage can also benefit public and individual health by facilitating physical activities such as walking or cycling to the metro station.
View Article and Find Full Text PDFPrevious studies manifested that the majority of structures that exhibit nonreciprocal thermal radiation in the mid-infrared are capable of achieving either single-band strong nonreciprocity or multi-band weak nonreciprocity at a large incidence angle. However, few structures can realize multi-band strong nonreciprocity at a small incidence angle. To address such scientific issues, we propose a tunable nonreciprocal thermal emitter based on gallium arsenide (GaAs)/graphene/Weyl semimetal (WSM).
View Article and Find Full Text PDFBackground: Depression and anxiety are common psychiatric symptoms in patients with Chronic Obstructive Pulmonary Disease (COPD). While face-to-face psychotherapy is a common option, tele-based interventions provide a more accessible alternative. However, a comprehensive synthesis of evidence from clinical trials for COPD patients has yet to be conducted.
View Article and Find Full Text PDFBackground: Alzheimer's disease (AD) is a degenerative disorder of the central nervous system characterized by notable pathological features such as neurofibrillary tangles and amyloid beta deposition. Additionally, the significant iron accumulation in the brain is another important pathological hallmark of AD. Exercise can play a positive role in ameliorating AD, but the mechanism is unclear.
View Article and Find Full Text PDFBackground: Depression and anxiety are common mental disorders in later life. Digital intelligence interventions overcome the limitations of conventional psychotherapy and offer new treatments for depression and anxiety. However, the effectiveness among older adults remains unclear.
View Article and Find Full Text PDFSmartphone distraction (SD) is closely related to depression, and the prevalence of SD among nursing students is gradually increasing. However, the potential mechanism of the effect of SD on nursing students' depression is unclear. A total of 574 nursing students were assessed using Smartphone Distraction Scale, Ruminative Response Scale, Hikikomori Questionnaire, and Patient Health Questionnaire-9.
View Article and Find Full Text PDFCircular dichroism (CD) spectrum and optical rotation (OR) spectrum, crucial for understanding molecular properties and configurations, present challenges due to limited testing methods and equipment accuracy in the ultraviolet (UV) region. This study proposes a weak measurement system for chiral signals in varying concentrations in the ultraviolet range, optimized using a deep neural network (DNN) model. Introducing different post-selections to detect the circular dichroism spectrum and optical rotation spectrum separately, with contrast as a probe, it achieves a detection resolution of up to 10 rad.
View Article and Find Full Text PDFBackground: Identifying high-risk populations and promoting stroke prevention measures can be achieved through studies on stroke and its risk factors. As a new alternative indicator of insulin resistance (IR), the triglyceride glucose (TyG) index may potentially increase stroke risk. However, the evidence confirming this association is inadequate and inconsistent, possibly due to variations in stroke assessment criteria or characteristics of the study populations.
View Article and Find Full Text PDFThe Internet of Things (IoT) plays an essential role in people's daily lives, such as healthcare, home, traffic, industry, and so on. With the increase in IoT devices, there emerge many security issues of data loss, privacy leakage, and information temper in IoT network applications. Even with the development of quantum computing, most current information systems are weak to quantum attacks with traditional cryptographic algorithms.
View Article and Find Full Text PDFMetasurface zone plates exhibit stronger optical control capabilities than traditional Fresnel zone plates, especially in polarization transformation and multiplexing. However, there are still few studies on metasurface zone plates that can be used for simultaneous control of forward and backward waves. In this work, we propose what is to our knowledge a new scheme that utilizes metasurface zone plates for orthogonal linear polarization separation and wavefront manipulation at the same time.
View Article and Find Full Text PDFObjective: This study aims to explore the psychological distress course of Chinese amyotrophic lateral sclerosis (ALS) patients after the onset of the disease and to provide targeted nursing guidance.
Design: The interview content was analysed qualitatively. We used seven steps of Colaizzi's method to analyse the participants' data.
Background: Necroptosis has emerged as a novel molecular pathway that can be targeted by chemotherapy agents in the treatment of cancer. OSW-1, which is derived from the bulbs of Baker, exerts a wide range of pharmacological effects.
Aim: To explore whether OSW-1 can induce necroptosis in colorectal cancer (CRC) cells, thereby expanding its range of clinical applications.
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of the joints and bone destruction. Because of systemic administration and poor targeting, traditional anti-rheumatic drugs have unsatisfactory treatment efficacy and strong side effects, including myelosuppression, liver or kidney function damage, and malignant tumors. Consequently, mesenchymal stem cells (MSCs)-involved therapy is proposed for RA therapy as a benefit of their immunosuppressive and tissue-repairing effects.
View Article and Find Full Text PDFWith the rapid development of 5G communication technology, microwave dielectric ceramics with high dielectric constants are very conducive to the miniaturization of passive devices. Here, BaTi(NiNb)NbO (BTN ∼ NN, 0.03 ≤ ≤ 0.
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