The benefits of physical exercise on older adults' cognitive function: A cohort study exploring potential mechanisms.

Background: Despite existing studies showing that physical exercise improves cognitive function in older adults either concurrently or in a delayed manner, studies examining these associations simultaneously are rare. Additionally, the underlying mechanisms in these associations remain incompletely understood.

Objective: This study explores the concurrent and delayed (two years later) associations between physical exercise and older adults' cognitive function.

Cyberbullying victimization and perpetration: The influence on cyberostracism and youth anxiety.

Cyberbullying is considered a major threat to adolescent anxiety. In this study, we aim to explore the simultaneous effects of cyberbullying victimization and perpetration on youth anxiety. Building on the childhood adversity model and the vulnerability-stress model, we test the model wherein cyberbullying exposure is linked with cyberostracism, which in turn is expected to be associated with an increase in anxiety.

Pandemic Stress and Cyberbullying Among Adolescents During China's Outbreak of Omicron: Examining the Roles of Perceived Safety and Family Cohesion.

The COVID-19 pandemic posed risks to the psychosocial development of children and adolescents in the digital age. Under such a background, this study aims to examine the effects of pandemic stress on cyberbullying perpetration and victimization among Chinese adolescents, and to explore the mediator of perceived safety and the moderator of family cohesion underlying this association, during China's outbreak of Omicron. A sample of 822 adolescents was obtained from Taizhou in Zhejiang Province, China, based on a multistage cluster random sampling method.

The relationship between bullying victimization and problematic behaviors: A focus on the intrapersonal emotional competence and interpersonal social competence.

Background: Evidence consistently demonstrated that bullying victimization was associated with problematic behaviors among adolescents. However, scant attention has been given to simultaneous comparisons of the impacts of two distinct forms of victimization, traditional bullying victimization and cyberbullying victimization. In addition, the mechanisms underlying the relationship between bullying victimization and problem behavior remain inadequately explored.

Exploring the associations between competence in dementia care and work attitudes among formal caregivers in nursing homes.

Aims: Based on the two-factor model of caregiving appraisals, this study aims to (1) investigate the relationships between competence in dementia care and job satisfaction (work attitudes in positive aspect) and turnover intention (work attitudes in negative aspect) among formal caregivers in nursing homes, and (2) examine the mediating roles of positive aspects of caregiving (caregiving appraisals in positive aspect) and caregiving burden (caregiving appraisals in negative aspect) in the above associations.

Design: A cross-sectional design was used. Structural equation modelling was employed to test the proposed model.

Factors mitigate the effect of widowhood's mental health impact: A longitudinal test from individual, familial, and social perspectives.

Although widowhood has been considered a significant risk factor for mental health, the duration of its effects and the potential mitigating factors involved in this relationship remain inadequately understood among Chinese older adults. This study investigates the longitudinal relationship between widowhood and depression and examines the interaction effects of health asymmetry, the number of children, and urban-rural differences from individual, familial, and social perspectives. A sample of 9,563 individuals for the four rounds period (from 2011 to 2018) is obtained from the China Health and Retirement Longitudinal Study.

The Long Arm of Childhood Bullying Victimization: Associations with Social Isolation, Gender Differences and Depression in Later Life.

The association between childhood bullying victimization and depression has been well-explored among young adults, but little is known about whether this relationship persists into later life stages, specifically during middle-aged and older phases. Moreover, the intricate mechanisms underpinning this association and the potential existence of gender differences within this context remain inadequately elucidated. To address this gap in knowledge, this study aims to investigate the association between childhood bullying victimization and depression in later life, with a focus on exploring the mediating role of social isolation and the moderating roles of gender.

Community support, social isolation and older adults' life satisfaction: evidence from a national survey in China.

Objectives: Despite the recognized importance of community social service and community built facility for enhancing older adults' life satisfaction, the mechanisms underlying their relationship have not been thoroughly examined. This study aims to complement the existing knowledge by investigating the mediating role of social disconnectedness and loneliness in the association between community support and life satisfaction among older adults.

Methods: Using data from the 2018 China Longitudinal Aging Social Survey, the study analyzes responses from 9,874 Chinese older adults (mean age = 71.

Multimode-Responsive Luminescence of Er Single-Activated CaF Phosphor for Advanced Information Encryption.

The current optical anticounterfeit strategies that rely on multimode luminescence in response to the photon or thermal stimuli have significant importance in the field of anticounterfeiting and information encryption. However, the dependence on light and heat sources might limit their flexibility in practical applications. In this work, Er single-doped CaF phosphors that show multistimuli-responsive luminescence have been successfully prepared.

The impact of widowhood on mental health of older adults.

Widowhood is identified as a risk factor for older adults' mental health, however, the underlying mechanisms and protective factors in this association has not been fully revealed. In order to add to the current knowledge, this study investigates the mediating roles of economic, social and psychological resources and the moderating role of community support in the relationship between widowhood and mental health. A sample of 7913 Chinese older people (Mean age = 71.

Linking chronic diseases, cognitive impairment and depressive symptoms in Chinese older adults: A three-wave population-based longitudinal study.

Objective: Despite previous studies illustrate that chronic diseases are risk factors for older adults' psychological health, little is known about its mediating mechanism. This study aims to examine the mediating effect of cognitive impairment. Also, a particular emphasis is placed on whether the Hukou system in China contributes to the adverse effect of chronic diseases on depressive symptoms.

Examining the mediator and moderator of the link between Migration-Related stress and depression amongst Chinese migrant children.

Migration-related stress is detrimental to children's mental health, yet little is known about the potential mechanisms behind this association. This study examines the mediating role of inflow city identity in the association between migration-related stress and depression and the moderating role of social participation amongst Chinese migrant children. A sample of 484 migrant children aged 8-17 years is randomly recruited through a cross-sectional survey in Kunming, China.

The Association of Body Mass Index With Mortality Among Pulmonary Hypertension Patients: A Systematic Review and Meta-Analysis of Cohort Studies.

Objective: To run a systematic review and meta-analysis of related studies on body mass index (BMI) and the risk of death among pulmonary hypertension (PH) patients, as well as, to shed light on the shape and strength of the dose-response association.

Methods: Studies published up to Jun 2021 in scientific databases such as Scopus, and PubMed as well as Google Scholar were searched. Cohort studies that reported risk estimates for at least two categories of BMI or per certain increase in BMI in relation to mortality in PH patients were included.

Effects of Adverse Childhood Experiences on Late-life Mental Health: Potential Mechanisms Based on a Nationally Representative Survey in China.

Adverse childhood experiences (ACEs) are risk factors in the mental health of older adults; however, little is known about its underlying mechanisms. This study investigates the mediating role of physical and cognitive functions and the moderating role of number of children in the association between ACEs and mental health. A sample of 8,494 Chinese older adults are drawn from the 2018 China Longitudinal Aging Social Survey.

Stressful Life Events and Life Satisfaction among Chinese Older Adults: The Role of Coping Styles.

This study aims to investigate the mediating effect of coping styles in the relationship between stressful life events and life satisfaction among Chinese older adults. To test the hypotheses, cross-sectional data ( = 8799) from the 2016 China Longitudinal Aging Social Survey (CLASS) were analyzed by Stata 15/SE in this study. Results indicated that stressful life events directly affected life satisfaction.

Elder mistreatment and life satisfaction of older adults: mediating roles of emotional closeness with children and loneliness.

Elder mistreatment is a risk factor in the life satisfaction of older adults, yet understanding of its underlying mechanisms remains limited. This study investigates the mediating role of emotional closeness and loneliness in the association between elder mistreatment and life satisfaction. A sample of 8,717 Chinese older adults is obtained from the 2018 China Longitudinal Aging Social Survey.

Academic stress and depression of Chinese adolescents in junior high schools: Moderated mediation model of school burnout and self-esteem.

Background Despite previous research indicates that academic stress is a risk factor for students' mental health, the mediating and moderating mechanisms underlying this relationship are less known. This study tests the mediation effect of school burnout in the association between academic stress and adolescent depression, and whether this mediation is moderated by self-esteem. Methods A sample of 552 Chinese adolescents in junior high schools (mean age = 14.

Downregulation of Long Noncoding RNA LINC00261 Attenuates Myocardial Infarction through the miR-522-3p/Trinucleotide Repeat-Containing Gene 6a (TNRC6A) Axis.

Background: Myocardial infarction (MI) is cardiac tissue necrosis caused by acute and persistent ischemic hypoxia of the coronary arteries. This study is aimed at investigating the expression of long noncoding RNA (lncRNA) LINC00261 in MI and its effect on myocardial cells.

Methods: qRT-PCR was performed to detect the expression levels of LINC00261, miR-522-3p, and TNRC6A in normal and MI cells.

Examining the link between economic strain and adolescent social behavior: Roles of social bonds and empathy.

Introduction: The detrimental effect of economic strain on adolescent behavioral development is well established, but the mechanisms explaining this relationship are less known. This study aims to explore the psychosocial factors operating as pathways connecting economic strain to adolescent antisocial and prosocial behaviors, and examine whether these effects differ by gender.

Methods: The sample includes 1280 adolescents from middle and high schools in Hebei province, China (Mean age = 15.

Dysregulated Serum MiRNA Profile and Promising Biomarkers in Dengue-infected Patients.

Objectives: Pathological biomarkers and mechanisms of dengue infection are poorly understood. We investigated a new serum biomarker using miRNAs and performed further correlation analysis in dengue-infected patients.

Methods: Expression levels of broad-spectrum miRNAs in serum samples from three patients with dengue virus type 1 (DENV-1) and three healthy volunteers were separately analyzed using miRNA PCR arrays.

[Alterations of peripheral blood endothelial progenitor cells from patients with ST elevation myocardial infarction after snake venom fibrinolytic enzyme therapy].

Objective: To investigate the morphological and quantitative alterations of peripheral blood endothelial progenitor cells (EPCs) in patients with ST elevation myocardial infarction (STEMI) after snake venom fibrinolytic enzyme therapy.

Methods: Sixty patients with STEMI and 20 control patients free of STEMI were enrolled in this study. The mononuclear cells were isolated from the peripheral blood of the STEMI patients before and 3 and 7 days after fibrinolytic enzyme injection.

[Relationship of angiotensin-converting enzyme 2 gene polymorphisms and vulnerability to coronary heart disease in patients with type 2 diabetes mellitus].

Objective: To investigate the association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms and coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM).

Methods: This study involved 121 patients with T2DM and 94 with diabetic macroangiopathy. The polymorphisms of G8790A in ACE2 gene was analyzed using PCR-restriction fragment length polymorphism analysis in these patients, and the clinical, biochemical and echocardiographic data were also analyzed.

[Detection of high-sensitivity C-reactive protein and total cholesterol/high-density lipoprotein cholesterol ratio for diagnosis of coronary artery disease].

Objective: To study the value of detecting high-sensitivity C-reactive protein (hs-CRP) combined with determination of total cholesterol/high-density lipoprotein cholesterol (TC/HDL-C) in the diagnosis of coronary artery disease (CHD).

Methods: A total of 240 patients with documented CHD and 40 healthy subjects were enrolled in this study for measurement of serum concentrations of hs-CRP, TC and HDL-C.

Results: The concentration of hs-CRP and TC/HDL-C ratio was significantly higher in CHD patients than in the control subjects (P<0.