Faecal metaproteomics analysis reveals a high cardiovascular risk profile across healthy individuals and heart failure patients.

The gut microbiota is a crucial link between diet and cardiovascular disease (CVD). Using fecal metaproteomics, a method that concurrently captures human gut and microbiome proteins, we determined the crosstalk between gut microbiome, diet, gut health, and CVD. Traditional CVD risk factors (age, BMI, sex, blood pressure) explained < 10% of the proteome variance.

Research on dynamic urine volume detection system based on smart flexible textile sensors.

Urine leakage volume is an important indicator reflecting the severity of incontinence in patients. Currently, there are limited smart diapers capable of continuous dynamic monitoring of urine volume. This study developed two types of urine volume sensors, resistive and capacitive, which were integrated with traditional diapers to assess urine leakage levels: mild leakage (0-5 mL), moderate leakage (6-12 mL), and severe leakage (above 12 mL).

Selective CO electroreduction to formate over a Cu-based catalyst in S-containing electrolyte.

A CuO-derived catalyst selectively and durably electroreduces CO to formate with a maximum faradaic efficiency of 74% in S-containing electrolyte and exhibits a high formate partial current density of up to 110 mA cm in a flow cell.

Effects of long-term different-scale rice-duck farming on the growth and yield of paddy rice.

Background: To maintain rice production and increase revenue, rice-duck (RD) farming is a contemporary ecological cycle technology that has been widely used in Asia. However, due to the clustering activity of duck flocks, the consequences of long-term RD farming on rice growth at different scales are still unknown. Here, we studied RD farming using several different treatments (CK: conventional rice farming; RD1: 667 m ; RD2: 2000 m ; and RD3: 3333 m ).

Release characteristic of bound polyphenols from tea residues insoluble dietary fiber by mixed solid-state fermentation with cellulose degrading strains CZ-6 and CZ-7.

The purpose of this work was to investigate the release characteristic of bound polyphenols (BP) from tea residues insoluble dietary fiber (IDF) by mixed solid-state fermentation (SSF) with cellulose degrading strains CZ-6 and CZ-7. The results implied that cellulase, β-glucosidase and filter paper lyase activities were strongly correlated with the BP content. The scanning electron microscop and fourier transform infrared spectroscopy manifested that the cellulose network of the IDF was decomposed and dissolve, forming more loose fibrous structure.

Physicochemical Characteristics of Soluble Dietary Fiber Obtained from Grapefruit Peel Insoluble Dietary Fiber and Its Effects on Blueberry Jam.

Appropriate modification methods can increase the proportion of soluble dietary fiber (SDF). In this study, grapefruit peel insoluble dietary fiber (GP-IDF) was modified with the combined microwave and enzymatic method to obtain SDF. With regard to structural characterization, SDF from grapefruit peel IDF (GP-IDF-SDF) presented as a flat sheet with cracks, composed of a typical cellulose type I crystal, and had good stability below 200 °C.

Radiomics features of DSC-PWI in time dimension may provide a new chance to identify ischemic stroke.

Ischemic stroke has become a severe disease endangering human life. However, few studies have analyzed the radiomics features that are of great clinical significance for the diagnosis, treatment, and prognosis of patients with ischemic stroke. Due to sufficient cerebral blood flow information in dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) images, this study aims to find the critical features hidden in DSC-PWI images to characterize hypoperfusion areas (HA) and normal areas (NA).

Improving the physicochemical and hypolipidemic properties of soluble dietary fiber in camellia seed residue by a cellulose degrading fungus YC49.

Camellia seed residue (CSR) is the main by-product after edible oil extraction from camellia seed, which is a potential low-cost source of soluble dietary fiber (SDF). However, the lower yield and functional properties limit the further application of CSR SDF in the food industry. To fully utilize this resource, in this study, the cellulose degrading fungus YC49 was screened and used to modify SDF in CSR.

MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis.

Protein kinase A promotes beige adipogenesis downstream from β-adrenergic receptor signaling by phosphorylating proteins, including histone H3 lysine 9 (H3K9) demethylase JMJD1A. To ensure homeostasis, this process needs to be reversible however, this step is not well understood. We show that myosin phosphatase target subunit 1- protein phosphatase 1β (MYPT1-PP1β) phosphatase activity is inhibited via PKA-dependent phosphorylation, which increases phosphorylated JMJD1A and beige adipogenesis.

Screen of high efficiency cellulose degrading strains and effects on tea residues dietary fiber modification: Structural properties and adsorption capacities.

In our study, two high efficiency cellulose degrading strains were screened, isolated and identified as Cochliobolus kusanoi and Aspergillus puulaauensis by 18S rDNA gene sequencing. In addition, the composite microbial system was constructed to develop the synergistic effect among different strains. Under the optimum conditions, the yield of soluble dietary fiber from tea residues by mixed fermentation method (MF-SDF) dramatically increased compared to single strain fermentation.

A new approach to automatic measure fetal head circumference in ultrasound images using convolutional neural networks.

Fetal head circumference (HC) is an important biological index in prenatal ultrasound screening. In the clinic, fetal HC is usually measured manually by sonographers in two dimensional (2D) ultrasound images. The manual method is significantly affected by the inter/intra-observer difference and the process of manual measurement is inconvenient and time-consuming for sonographers.

Surface Transformation Enables a Dendrite-Free Zinc-Metal Anode in Nonaqueous Electrolyte.

Significant challenges remain in developing rechargeable zinc batteries mainly because of reversibility problems on zinc-metal anodes. The dendritic growth and hydrogen evolution on zinc electrodes are major obstacles to overcome in developing practical and safe zinc batteries. Here, a dendrite-free and hydrogen-free Zn-metal anode with high Coulombic efficiency up to 99.

Physicochemical structure and functional properties of soluble dietary fibers obtained by different modification methods from Mesona chinensis Benth. residue.

Alkaline hydrogen peroxide (AHP), high-temperature cooking combined with ultrasonic (HTCU) and high-temperature cooking combined with complex enzyme hydrolysis (HTCE) were used to modify soluble dietary fiber (SDF) in Mesona chinensis Benth. residue (MCBR), then the structural and in vitro functional properties of A-SDF, HU-SDF and HE-SDF were investigated. Results showed that the three treatments significantly increased the yield of SDF.

RDHCformer: Fusing ResDCN and Transformers for Fetal Head Circumference Automatic Measurement in 2D Ultrasound Images.

Fetal head circumference (HC) is an important biological parameter to monitor the healthy development of the fetus. Since there are some HC measurement errors that affected by the skill and experience of the sonographers, a rapid, accurate and automatic measurement for fetal HC in prenatal ultrasound is of great significance. We proposed a new one-stage network for rotating elliptic object detection based on anchor-free method, which is also an end-to-end network for fetal HC auto-measurement that no need for any post-processing.

A novel lung radiomics feature for characterizing resting heart rate and COPD stage evolution based on radiomics feature combination strategy.

The resting HR is an upward trend with the development of chronic obstructive pulmonary disease (COPD) severity. Chest computed tomography (CT) has been regarded as the most effective modality for characterizing and quantifying COPD. Therefore, CT images should provide more information to analyze the lung and heart relationship.

Light-Induced Redox Looping of a Rhodium/Ce WO Photocatalyst for Highly Active and Robust Dry Reforming of Methane.

Dry reforming of methane (DRM) has provided an effective avenue to convert two greenhouse gases, CH and CO , into syngas. Here, we design a DRM photocatalyst Rh/Ce WO that invokes both photothermal and photoelectric processes, which overcomes the thermodynamic limitation of DRM under conventional conditions. In contrast to plasmonic or UV-response photocatalysts, our photocatalyst produces a superior light-to-chemical energy efficiency (LTCEE) of 4.

Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis.

Enhancer activation is essential for cell-type specific gene expression during cellular differentiation, however, how enhancers transition from a hypoacetylated "primed" state to a hyperacetylated-active state is incompletely understood. Here, we show SET domain-containing 5 (SETD5) forms a complex with NCoR-HDAC3 co-repressor that prevents histone acetylation of enhancers for two master adipogenic regulatory genes Cebpa and Pparg early during adipogenesis. The loss of SETD5 from the complex is followed by enhancer hyperacetylation.

Hybrid MgCl/AlCl/Mg(TFSI) Electrolytes in DME Enabling High-Rate Rechargeable Mg Batteries.

Rechargeable magnesium batteries (RMBs) are considered as one of the most promising next-generation secondary batteries due to their low cost, safety, dendrite-free nature, as well as high volumetric energy density. However, the lack of suitable cathode material and electrolyte is the greatest challenge facing practical RMBs. Herein, a hybrid electrolyte MgCl/AlCl/Mg(TFSI) (MACT) in dimethyl ether (DME) is developed and exhibits excellent electrochemical performance.

Modeling and simulation of musculoskeletal system of human lower limb based on tensegrity structure.

In this paper, a mechanical model of the skeletal muscle of human lower limb system is established by using the Hill muscle model and kinetic equation of the movement of lower extremities according to the attachment positions of skeletal muscle. State vector and neural control are delineated by the direct configuration method. Changes of gait and skeletal muscle stress during walking process are analyzed with energy consumption as objective function.

Electrochemical-Conditioning-Free and Water-Resistant Hybrid AlCl /MgCl /Mg(TFSI) Electrolytes for Rechargeable Magnesium Batteries.

Rechargeable magnesium batteries are a promising alternative to Li-based energy storage because of their abundant and inexpensive components. The high sensitivity and reactivity of the organic Mg electrolyte makes their development challenging. Herein, we develop a new hybrid electrolyte, based on three simple inorganic salts of MgCl , AlCl , and Mg(TFSI) .

[The acceleration algorithm for projection decomposition of dual-energy computed tomography image reconstruction based on projection matching].

Dual-energy computed tomography (CT) reconstruction imaging technology is an important development direction in the field of CT imaging. The mainstream model of dual-energy CT reconstruction algorithm is the basis material decomposition model, and the projection decomposition is the crucial technique. The projection decomposition algorithm based on projection matching was a general method.