Synopsis of recent research by authors named "Chaoran Shi"
- Chaoran Shi's recent research focuses heavily on spinal cord injury (SCI), exploring various mechanisms and therapeutic approaches to promote vascular and neural repair, particularly highlighting the role of endothelial cells and macrophages in the injury response.
- Key findings include the identification of specific vascular changes during chronic SCI, such as endothelial-to-mesenchymal transition and the potential of targeting metabolic disruptions through lactate shuttles to enhance axon regeneration.
- Shi's studies also investigate innovative strategies like mitochondrial transplantation and the modulation of macrophage polarization using endothelial progenitor cell-derived exosomes to support recovery and reduce inflammation post-injury.
