Publications by authors named "Chaoqun Luo"
Saprolegniasis caused by Saprolegnia parasitica leads to significant economic losses in the aquaculture industry worldwide. Effector proteins secreted by pathogens are key molecules involved in their pathogenicity and long non-coding lncRNAs (lncRNAs) act as regulators in these processes. However, little is known about the lncRNAs and effector proteins in S.
View Article and Find Full Text PDFPhotocytotoxicity represents a significant limitation in the application of dye-assisted fluorescence imaging (FI), often resulting in undesirable cellular damage or even cell death, thereby restricting their practical utility. The prevalence of Rhodamine B (RhB) in FI underscores the importance of elucidating its photocytotoxicity effects to minimize photodamage. This study identifies the primary cause of photocytotoxicity stems from the generation of cytotoxic singlet oxygen in RhB, utilizing femtosecond transient absorption spectroscopy coupled with quantum chemical calculations.
View Article and Find Full Text PDFArticle Synopsis
- The study documents the use of traditional animal- and mineral-based medicines among diverse ethnic groups in the Gansu-Ningxia-Inner Mongolia junction zone, aiming to explore their potential for sustainable development and further research.
- A total of 47 animal-based and 12 mineral-based medicines were identified, with significant insights gained from interviews with 56 informants, particularly highlighting the expertise of female local herbal practitioners.
- Key findings emphasize the cultural importance of specific medicines like Feng-Mi and Xie-Zi, and the study underscores the need for preserving these practices for the holistic well-being of local communities.
Objective: The utility of metagenomic next-generation sequencing (mNGS) in the diagnosis of tuberculous meningitis (TBM) remains uncertain. We performed a meta-analysis to comprehensively evaluate its diagnostic accuracy for the early diagnosis of TBM.
Methods: English (PubMed, Medline, Web of Science, Cochrane Library, and Embase) and Chinese (CNKI, Wanfang, and CBM) databases were searched for relevant studies assessing the diagnostic accuracy of mNGS for TBM.
Article Synopsis
- Tuberculous meningitis (TBM) is the leading form of central nervous system tuberculosis, associated with high rates of mortality and disability, making early diagnosis crucial for improving patient outcomes.
- The traditional diagnostic methods for TBM, which include microscopy, culture, and PCR, are often ineffective due to the low bacterial load in the cerebrospinal fluid (CSF) and the limitations of conventional techniques.
- This review highlights the current landscape of TBM diagnostics, emphasizing ongoing research, the pros and cons of available methods, and the challenges clinicians face in ensuring accurate and efficient diagnosis.
Introduction: This study conducted an ethnobotanical survey of wild medicinal plants in the multi-ethnic areas of Gansu-Ningxia-Inner Mongolia intersection zone. Traditional knowledge of medicinal plant use in the region was compiled to identify important medicinal plants currently used for treating relevant diseases and to determine species with potential for development.
Methods: Key informant interviews, semi-structured interviews, participatory rural appraisal methods, and ethnobotanical quantitative evaluation were used to investigate and study the traditional knowledge of local residents' use of wild medicinal plants in the region.
Background: Tuberculous meningitis (TBM) is the most serious form of extrapulmonary tuberculosis caused by , and is characterized by high morbidity and mortality. Unfortunately, it is difficult to distinguish TBM from bacterial meningitis (BM) based on clinical features alone. The latest diagnostic tests and neuroimaging methods are still not available in many developing countries.
View Article and Find Full Text PDFObjective: This study aims to explore the effect of TREM2 modified BMSCs on hippocampus of AD mice.
Methods: Mouse bone marrow mesenchymal stem cells were isolated and identified. APP/PS1 double transgenic mice were confirmed to be AD model and divided into 4 groups: control group, MSCs group, MSCs+vector group and MSCs+pEGFP-TREM2 group.