Multidimensional conservation analysis decodes the expression of conserved long noncoding RNAs.

Although long noncoding RNAs (lncRNAs) experience weaker evolutionary constraints and exhibit lower sequence conservation than coding genes, they can still conserve their features in various aspects. Here, we used multiple approaches to systemically evaluate the conservation between human and mouse lncRNAs from various dimensions including sequences, promoter, global synteny, and local synteny, which led to the identification of 1,731 conserved lncRNAs with 427 high-confidence ones meeting multiple criteria. Conserved lncRNAs, compared with non-conserved ones, generally have longer gene bodies, more exons and transcripts, stronger connections with human diseases, and are more abundant and widespread across different tissues.

Broadband tunable single-longitudinal-mode erbium-doped fiber ring laser based on a microfiber knot resonator.

We propose and demonstrate a broadband tunable single-longitudinal-mode (SLM) erbium-doped fiber laser based on a microfiber knot resonator (MKR). The MKR is made from a double-ended fiber taper and employed for SLM filtering based on the Vernier effect. An unpumped erbium-doped fiber is used in the fiber laser cavity to suppress mode-hopping for a stabilized SLM laser operation.

[Electroacupuncture of Hegu(LI 4) and Sanyinjiao(SP 6) Assists Medicinal Abortion].

Objective: To observe the effectiveness of electroacupuncture (EA) therapy in promoting medicinal abortion.

Methods: Sixty participants with early pregnancy were randomly divided into medication (control) and EA+ medication groups (=30 in each). Participants in the control group were treated by regular medication (mifepristone and misoprostol tablets), and those of the EA group were treated by EA stimulation (2 Hz/100 Hz, a tolerable strength) of bilateral Hegu(LI 4) and Sanyinjiao(SP 6) for 25 min, and also by the same medication method mentioned in the control group.

Prevalence and clinical characteristics of active epilepsy in southern Han Chinese.

Purpose: To investigate the prevalence and clinical characteristics of active epilepsy in southern Han Chinese.

Method: A door-to-door survey about epilepsy was conducted in communities identified by random cluster sampling among 20 villages and 3 communities of Yueyang city. A questionnaire for epilepsy based on the World Health Organization screening questionnaire was used.

Investigation of prevalence, clinical characteristics and management of epilepsy in Yueyang city of China by a door-to-door survey.

Background: The aim of this study was to establish the prevalence rate, types and causes of epilepsy, and information on treatment gap of epilepsy in Yueyang city, and to evaluate the diagnosis and treatment status of these patients.

Methods: A door-to-door epidemiological survey on epilepsy was conducted by random cluster sampling among the urban and rural populations of Yueyang city, Hunan province, China. The screening questionnaire for epilepsy used in this study was adapted from the WHO and ICBERG standard screening questionnaires.