Publications by authors named "Chaoqing Zhang"

Background And Aims: Adolescent major depressive disorder (MDD) is prevalent globally but often goes unnoticed due to differences in symptoms compared to adult criteria. Analyzing the brain from a network perspective provides new insights into higher-level brain functions and its pathophysiology. This study aimed to investigate changes in the topological organization of functional networks in adolescents with first-episode, treatment-naïve MDD.

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Article Synopsis
  • Puberty is a time when some kids can start feeling really sad, and this study looked at how changes in the brain during this time can relate to major depression in young people.
  • Researchers used special brain scans to compare kids with depression to healthy kids and found some important differences in their brain's white matter.
  • They also created a model that could help identify depression in kids based on brain scans and other information, showing that changes in brain structure can connect to how sad someone feels.
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Brain function relies on efficient communications between distinct brain systems. The pathology of major depressive disorder (MDD) damages functional brain networks, resulting in cognitive impairment. Here, we reviewed the associations between brain functional connectome changes and MDD pathogenesis.

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