Phospholipid transfer protein ameliorates sepsis-induced cardiac dysfunction through NLRP3 inflammasome inhibition.

Cardiomyocyte pyroptosis is a primary contributor to sepsis-induced cardiac dysfunction (SICD). Recombinant phospholipid transfer protein (PLTP) have been demonstrated to possess anti-inflammatory and antiseptic properties. However, the effect of PLTP on SICD remains unknown.

A Novel P/N/Si-Containing Vanillin-Based Compound for a Flame-Retardant, Tough Yet Strong Epoxy Thermoset.

It is still extremely challenging to endow epoxy resins (EPs) with excellent flame retardancy and high toughness. In this work, we propose a facile strategy of combining rigid-flexible groups, promoting groups and polar phosphorus groups with the vanillin compound, which implements a dual functional modification for EPs. With only 0.

LDH@Boronate Polymer Core-Shell Nanoparticles: Nanostructure Design for Synergistically Enhancing the Flame Retardancy of Epoxy Resin.

As a promising nanofiller, layered double hydroxides (LDHs) can advance the fire safety of epoxy resin (EP), but so far, due to the problems of dispersion and low efficiency, it has still been a challenge to incorporate the flame retardancy and mechanical properties of EP nanocomposites effectively under the circumstance of a low additive amount. In this work, we take LDHs as the template, via the adsorption of a catechol group and the condensation polymerization between catechol groups and phenylboric acid groups, to prepare a core-shell structured nanoparticle LDH@BP, which contains rich flame-retardant elements. EP/LDH@BP nanocomposites were prepared by introducing LDH@BP into EP.

A Novel Anderson-Type POMs-Based Hybrids Flame Retardant for Reducing Smoke Release and Toxicity of Epoxy Resins.

Smoke emission and smoke toxicity have drawn more attention to improving the fire safety of polymers. In this work, a polyoxometalates (POMs)-based hybrids flame retardant (P-AlMo ) epoxy resin (EP) is prepared with toxicity-reduction and smoke-suppression properties via a peptide coupling reaction between POMs and organic molecules with double DOPO (bisDOPA). It combines the good compatibility of the organic molecule and the superior catalytic performance of POMs.

Disaster Preparedness Among Nurses in China: A Cross-Sectional Study.

Background: Increasingly frequent global disasters such as coronavirus disease 2019 pose a threat to human health and life. The World Health Organization has called on countries to formulate detailed plans to prepare for disasters. It is critical to investigate and evaluate the disaster preparedness of nurses.

Relationship between perceived organizational support and professional values of nurses: mediating effect of emotional labor.

Objectives: Perceived organizational support was a benefit for the work performance of nurses, which may affect emotional labor and the development of professional values. This study aimed to explore the relationship between nurses' perceived organizational support and professional values, and investigate the mediating role of emotional labor.

Methods: This was a cross-sectional study.

Investigation on a high gravity device for reduction of NOx emission from marine diesel engines.

High gravity technology, as a process intensification technology, has demonstrated the great advantages in the field of gas purification on account of its excellent mass transfer efficiency and energy-efficient, but it is rarely applied in the field of nitrogen oxides (NOx) purification of marine diesel engine exhaust. In this paper, a high-gravity bowl-shaped-disk rotating bed (HBRB) without catalytic was designed for diesel exhaust after-treatment. A diesel oxidation catalyst (DOC) was installed in the front of the HBRB to regenerate more nitrogen dioxide (NO) easily reduced by urea.

Electrically programmable adhesive hydrogels for climbing robots.

Although there have been notable advances in adhesive materials, the ability to program attaching and detaching behavior in these materials remains a challenge. Here, we report a borate ester polymer hydrogel that can rapidly switch between adhesive and nonadhesive states in response to a mild electrical stimulus (voltages between 3.0 and 4.

Effect of pain on depression among nursing home residents: Serial mediation of perceived social support and self-rated health. A cross-sectional study.

Aim: The aim of this study was to investigate how perceived social support and self-rated health together could mediate the relationship between pain and depression among Chinese nursing home residents with pain.

Methods: The study was conducted in 38 nursing homes in 13 cities in China. A convenience sample of 2154 older adults responded to the questionnaire survey.

Nurses' Perceptions of Factors Influencing Elder Self-neglect: A Qualitative Study.

Purpose: Elder self-neglect is a global public health issue and should be taken seriously at large. Nurses, usually working directly with elderly patients, have a better understanding of what factors may cause elder self-neglect. In this qualitative study, we explored the influencing factors of elder self-neglect from the perception of nurses in the context of Chinese culture.

Emergency management of nursing human resources and supplies to respond to coronavirus disease 2019 epidemic.

Objective: To introduce the emergency management of nursing human resources and supplies of a large general hospital when facing the outbreak of coronavirus disease 2019(COVID-19).

Method: The Nursing Department of the hospital fully executed its functional authority to establish a three-level echelon of sustainable support, allocate human recourses dynamically, organize pre-service training, supervise the key working steps, formulate positive incentive methods, and deploy medical supplies scientifically.

Result: By taking these strategies, the hospital effectively improved the coping capacity of the nursing team and played a positive role in the prevention and treatment of COVID-19.

Evaluation of particle penetration factors based on indoor PM removal by an air cleaner.

The particle penetration factor is an important parameter to determine the concentration of indoor particles. In this paper, a mathematical model for calculating this parameter was established by combining with the decay of the indoor PM and CO concentrations measured in a bedroom with an air cleaner. The convergence of the penetration factors was analyzed under different working conditions.

Chronic lead exposure decreases the expression of Huntingtin-associated protein 1 (HAP1) through Repressor element-1 silencing transcription (REST).

Chronic lead (Pb) exposure has been shown to reduce the expression of some synaptic proteins which are involved in vesicular trafficking and affect presynaptic neurotransmitter release. However, the precise mechanisms by Pb impairs neurotransmitter release are still not well defined. In the current study, we aimed to elucidate the changes of Huntingtin-associated protein 1 (HAP1) in Pb exposed rats and PC12 cells models and its molecular mechanism.

Superhydrophobic and flame retardant cotton modified with DOPO and fluorine-silicon-containing crosslinked polymer.

Modification of cotton fabric to achieve superhydrophobic, self-cleaning and heat resistance is of particular interest for practical applications. Herein, a simple surface modification route is designed to introduce flame retardant component 9, 10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide (DOPO) and low surface energy crosslinked polymer network comprising both fluorine and silicon elements on the surface of cotton fabric. The modified cotton fabric shows characteristic of superhydrophobic property with water contact angle of 154.

The therapeutic effect of pelvic floor muscle exercise on urinary incontinence after radical prostatectomy: a meta-analysis.

Pelvic floor muscle exercise (PFME) is the most common conservative management for urinary incontinence (UI) after radical prostatectomy (RP). However, whether the PFME guided by a therapist (G-PFME) can contribute to the recovery of urinary continence for patients after RP is still controversial. We performed this meta-analysis to investigate the effectiveness of G-PFME on UI after RP and to explore whether the additional preoperative G-PFME is superior to postoperative G-PFME alone.

Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.

Huntington's disease (HD) is a neurodegenerative disease caused by a polyglutamine expansion in the huntingtin (Htt) protein. Mutant Htt causes synaptic transmission dysfunctions by interfering in the expression of synaptic proteins, leading to early HD symptoms. Synaptic vesicle proteins 2 (SV2s), a family of synaptic vesicle proteins including 3 members, SV2A, SV2B, and SV2C, plays important roles in synaptic physiology.