Publications by authors named "Chao-yan Yang"
Objective: To investigate the protective effects of Chinese medicine formulation Chaihu Shugan San (, CHSGS) on nonalcoholic fatty liver disease (NAFLD) in rats with insulin resistance (IR) and its molecular mechanisms.
Methods: Male Sprague-Dawley rats were randomly divided into six groups: the control group, the model group, Dongbao Gantai group (, DBGT, 0.09 g methionine/kg), CHSGS high-dose group (CHSG-H, 12.
Article Synopsis
- The study aimed to evaluate the antifungal properties of different extracts from Dryopteris fragrans by analyzing their effectiveness against dermatophytes.
- Four extracts were obtained through reflux extraction, and their antifungal activities were measured using specific laboratory methods.
- Results indicated that the 95% ethanol extract had the highest phloroglucinol content and the strongest antifungal effect compared to other extracts tested.
Objective: To study the effect of HGD on diabetic cardiomyopathy and its mechanism.
Methods: The T2-DM rats model was established by combining high fat diet with STZ. The blood glucose, insulin, myocardial fibrosis and TGF-beta1/Smad3 signaling pathway were observed; TGF-beta1 and Smad3 mRNA expression were detected by RT-PCR method, protein expression detected by immunohistochemical method.
Objective: To observe the effect of fufang zhenzhu tiaozhi capsule (FTZ) on lipid metabolism in atherosclerotic rabbits.
Methods: 50 rabbits were divided into five groups: normal control group, model group, simvastatin group, the high-dose group and low-dose group of FTZ. The atherosclerotic model was established by feeding the rabbits with high fat diet.
Objective: To investigate the anti-hypoxia active fraction of Xiangdan injection.
Methods: The anti-hypoxia experiment under normal pressure with mice was adopted on the basis of orthogonal design, and a support vector machine model was established for pharmacodynamics prediction of TCM prescriptions. Moreover, the anti-hypoxia active fraction of Xiangdan injection was determined by experimental confirmation.